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Determination of systolic blood pressure and heart rate in conscious mice by tail-cuff method.
Two apparatus of BP-2000 seriesII 6 channels (Visitech Systems, Apex, North Carolina, USA)
Number of animals: 9 mice/gender/genotype . Maximum age : 8 weeks
Evaluation of the electrical activity of the heart in anesthetized mice
Electrocardiogram ISO DAM8 amplifier (World Precision Instruments, USA) and Analogic-numeric conversion box (ITF16A/D converter, EMKA technologies, USA)
Number of animals: 7-9 mice/gender/genotype
Echocardiography is considered the first-line diagnostic test, from which subsequent imaging or interventions can be recommended.
The Vevo 2100 High-Frequency Ultrasound Systems have been developed specifically for use in small animal imaging and are ideally suited for mouse or rat echocardiography. With center operating frequencies ranging from 15MHz to 50MHz one imaging system can be used to assess cardiac function from embryo to adult in many commonly used small animal models.
Vevo imaging System (VISUALSONICS, Amsterdam, The Netherlands).
Number of animals: 7-9 mice/gender/genotype
Telemetry blood pressure and heart rate: continuous recording of the systolic, diastolic and mean blood pressure and heart rate in conscious mice.
Telemetry EKG: continuous recording of electrocardiogram in conscious mice.
24 channels Data Sciences International acquisition system with 24 RPC-1 telemetric probe
The radio-telemetry system consists in implants and receiver: telemetry implants for small animals transmit data to receiver via AM radio waves.
The receiver is the RPC-1 receiver - DSI
-The Data Exchange Matrix - DSI
-The Computer (Dell) - DSI
-The Data Acquisition and Analysis System (Dataquest) - DSI
Telemetry blood pressure and heart rate
The implantable telemetry, PA-C10 Device (transmitter), for blood pressure and heart rate - DSI
Telemetry EKG
The implantable telemetry devices (transmitters) – DSI ETA-F20 Device for Electrocardiogram
Number of animals: 8-10 mice/gender/genotype
Optimal body weight: 30g
