ICS publications in 2021 - Institut Clinique de la Souris


A resource of targeted mutant mouse lines for 5,061 genes. Birling MC, Yoshiki A, Adams DJ, Ayabe S, Beaudet AL, Bottomley J, Bradley A, Brown SDM, Bürger A, Bushell W, Chiani F, Chin HG, Christou S, Codner GF, DeMayo FJ, Dickinson ME, Doe B, Donahue LR, Fray MD, Gambadoro A, Gao X, Gertsenstein M, Gomez-Segura A, Goodwin LO, Heaney JD, Hérault Y, de Angelis MH, Jiang ST, Justice MJ, Kasparek P, King RE, Kühn R, Lee H, Lee YJ, Liu Z, Lloyd KCK, Lorenzo I, Mallon AM, McKerlie C, Meehan TF, Fuentes VM, Newman S, Nutter LMJ, Oh GT, Pavlovic G, Ramirez-Solis R, Rosen B, Ryder EJ, Santos LA, Schick J, Seavitt JR, Sedlacek R, Seisenberger C, Seong JK, Skarnes WC, Sorg T, Steel KP, Tamura M, Tocchini-Valentini GP, Wang CL, Wardle-Jones H, Wattenhofer-Donzé M, Wells S, Wiles MV, Willis BJ, Wood JA, Wurst W, Xu Y, Teboul L, Murray SA Nat Genet 2021 Apr;53(4):416-419 View on PubMed
Building the Future Therapies for Down Syndrome: The Third International Conference of the T21 Research Society Dierssen M.a,b,c · Herault Y.d · Helguera P.e · Martínez de Lagran M.a,c · Vazquez A.b · Christian B.f · Carmona-Iragui M.g,h · Wiseman F.i · Mobley W.j · Fisher E.M.C.k · Brault V.d · Esbensen A.l · Jacola L.M.m · Potier M.C.n · Hamlett E.D.o · Abbeduto L.p · del Hoyo Soriano L.p · Busciglio J.q · Iulita M.F.r · Crispino J.s · Malinge S.t · Barone E.u · Perluigi M.u · Costanzo F.v · Delabar J.M.n · Bartesaghi R.w · Dekker A.D.x · De Deyn P.x,y · Fortea Ormaechea J.g,h · Shaw P.A.z · Haydar T.F.z · Sherman S.L.A · Strydom A.B · Bhattacharyya A.f Molecular Syndromology 2021 MAY 2021
Characterization of the spontaneous degenerative mitral valve disease in FVB mice. Ayme-Dietrich E, Da Silva S, Bouabout GA, Arnoux A, Guyonnet J, Becker G, Monassier L Plos One 2021 ;16(9):e0257022 View on PubMed
Droplet digital PCR or quantitative PCR for in-depth genomic and functional validation of genetically altered rodents. Lindner L, Cayrou P, Rosahl TW, Zhou HH, Birling MC, Herault Y, Pavlovic G Methods 2021 Jul;191():107-119 View on PubMed
Dyrk1a gene dosage in glutamatergic neurons has key effects in cognitive deficits observed in mouse models of MRD7 and Down syndrome. Brault V, Nguyen TL, Flores-Gutiérrez J, Iacono G, Birling MC, Lalanne V, Meziane H, Manousopoulou A, Pavlovic G, Lindner L, Selloum M, Sorg T, Yu E, Garbis SD, Hérault Y Plos Genet 2021 Sep;17(9):e1009777 View on PubMed
HDAC inhibitor ameliorates behavioral deficits in Mecp2(308/y) mouse model of Rett syndrome. Lebrun N, Delépine C, Selloum M, Meziane H, Nectoux J, Herault Y, Bienvenu T Brain Res 2021 Dec 1;1772():147670 View on PubMed
High Resolution Episcopic Microscopy for Qualitative and Quantitative Data in Phenotyping Altered Embryos and Adult Mice Using the New "Histo3D" System. Wendling O, Hentsch D, Jacobs H, Lemercier N, Taubert S, Pertuy F, Vonesch JL, Sorg T, Di Michele M, Le Cam L, Rosahl T, Carballo-Jane E, Liu M, Mu J, Mark M, Herault Y Biomedicines 2021 Jul 1;9(7): View on PubMed
Importing genetically altered animals: ensuring quality. Birling MC, Fray MD, Kasparek P, Kopkanova J, Massimi M, Matteoni R, Montoliu L, Nutter LMJ, Raspa M, Rozman J, Ryder EJ, Scavizzi F, Voikar V, Wells S, Pavlovic G, Teboul L Mamm Genome 2021 Sep 18 View on PubMed
INFRAFRONTIER quality principles in systemic phenotyping. Ehlich H, Cater HL, Flenniken AM, Goncalves Da Cruz I, Mura AM, Ntafis V, Raess M, Selloum M, Stoeger C, Suchanova S, Vuolteenaho R, Brown SDM, Hérault Y, Hinttala R, Hrabě de Angelis M, Kollias G, Kontoyiannis DL, Malissen B, McKerlie C, Sedláček R, Wells SE, Zarubica A, Rozman J, Sorg T Mamm Genome 2021 Jul 30 View on PubMed
Integrative approach to interpret DYRK1A variants, leading to a frequent neurodevelopmental disorder. Courraud J, Chater-Diehl E, Durand B, Vincent M, Del Mar Muniz Moreno M, Boujelbene I, Drouot N, Genschik L, Schaefer E, Nizon M, Gerard B, Abramowicz M, Cogné B, Bronicki L, Burglen L, Barth M, Charles P, Colin E, Coubes C, David A, Delobel B, Demurger F, Passemard S, Denommé AS, Faivre L, Feger C, Fradin M, Francannet C, Genevieve D, Goldenberg A, Guerrot AM, Isidor B, Johannesen KM, Keren B, Kibæk M, Kuentz P, Mathieu-Dramard M, Demeer B, Metreau J, Steensbjerre Møller R, Moutton S, Pasquier L, Pilekær Sørensen K, Perrin L, Renaud M, Saugier P, Rio M, Svane J, Thevenon J, Tran Mau Them F, Tronhjem CE, Vitobello A, Layet V, Auvin S, Khachnaoui K, Birling MC, Drunat S, Bayat A, Dubourg C, El Chehadeh S, Fagerberg C, Mignot C, Guipponi M, Bienvenu T, Herault Y, Thompson J, Willems M, Mandel JL, Weksberg R, Piton A Genet Med 2021 Aug 3 View on PubMed
Introduction to mammalian genome special issue: the microbiome in human health and disease. Pavlovic G, Seong JK, Weinstock GM Mamm Genome 2021 Aug;32(4):205 View on PubMed
Microglia-specific knock-down of Bmal1 improves memory and protects mice from high fat diet-induced obesity. Wang XL, Kooijman S, Gao Y, Tzeplaeff L, Cosquer B, Milanova I, Wolff SEC, Korpel N, Champy MF, Petit-Demoulière B, Goncalves Da Cruz I, Sorg-Guss T, Rensen PCN, Cassel JC, Kalsbeek A, Boutillier AL, Yi CX Mol Psychiatry 2021 May 28 View on PubMed
Multi-influential genetic interactions alter behaviour and cognition through six main biological cascades in Down syndrome mouse models. Duchon A, Del Mar Muniz Moreno M, Martin Lorenzo S, Silva de Souza MP, Chevalier C, Nalesso V, Meziane H, Loureiro de Sousa P, Noblet V, Armspach JP, Brault V, Herault Y Hum Mol Genet 2021 May 28;30(9):771-788 View on PubMed
Pathogenesis of Anorectal Malformations in Retinoic Acid Receptor Knockout Mice Studied by HREM. Mark M, Teletin M, Wendling O, Vonesch JL, Féret B, Hérault Y, Ghyselinck NB Biomedicines 2021 Jun 28;9(7): View on PubMed
Reliable and robust droplet digital PCR (ddPCR) and RT-ddPCR protocols for mouse studies. Lindner L, Cayrou P, Jacquot S, Birling MC, Herault Y, Pavlovic G Methods 2021 Jul;191():95-106 View on PubMed
SCA7 Mouse Cerebellar Pathology Reveals Preferential Downregulation of Key Purkinje Cell-Identity Genes and Shared Disease Signature with SCA1 and SCA2. Niewiadomska-Cimicka A, Doussau F, Perot JB, Roux MJ, Keime C, Hache A, Piguet F, Novati A, Weber C, Yalcin B, Meziane H, Champy MF, Grandgirard E, Karam A, Messaddeq N, Eisenmann A, Brouillet E, Nguyen HHP, Flament J, Isope P, Trottier Y J Neurosci 2021 Jun 2;41(22):4910-4936 View on PubMed
Targeting the RHOA pathway improves learning and memory in adult Kctd13 and 16p11.2 deletion mouse models. Martin Lorenzo S, Nalesso V, Chevalier C, Birling MC, Herault Y Mol Autism 2021 Jan 13;12(1):1 View on PubMed

A resource of targeted mutant mouse lines for 5,061 genes.

Birling MC, Yoshiki A, Adams DJ, Ayabe S, Beaudet AL, Bottomley J, Bradley A, Brown SDM, Bürger A, Bushell W, Chiani F, Chin HG, Christou S, Codner GF, DeMayo FJ, Dickinson ME, Doe B, Donahue LR, Fray MD, Gambadoro A, Gao X, Gertsenstein M, Gomez-Segura A, Goodwin LO, Heaney JD, Hérault Y, de Angelis MH, Jiang ST, Justice MJ, Kasparek P, King RE, Kühn R, Lee H, Lee YJ, Liu Z, Lloyd KCK, Lorenzo I, Mallon AM, McKerlie C, Meehan TF, Fuentes VM, Newman S, Nutter LMJ, Oh GT, Pavlovic G, Ramirez-Solis R, Rosen B, Ryder EJ, Santos LA, Schick J, Seavitt JR, Sedlacek R, Seisenberger C, Seong JK, Skarnes WC, Sorg T, Steel KP, Tamura M, Tocchini-Valentini GP, Wang CL, Wardle-Jones H, Wattenhofer-Donzé M, Wells S, Wiles MV, Willis BJ, Wood JA, Wurst W, Xu Y, Teboul L, Murray SA
Nat Genet 2021 Apr;53(4):416-419

About ICS

A resource of targeted mutant mouse lines for 5,061 genes.

Building the Future Therapies for Down Syndrome: The Third International Conference of the T21 Research Society

Characterization of the spontaneous degenerative mitral valve disease in FVB mice.

Droplet digital PCR or quantitative PCR for in-depth genomic and functional validation of genetically altered rodents.

Dyrk1a gene dosage in glutamatergic neurons has key effects in cognitive deficits observed in mouse models of MRD7 and Down syndrome.

HDAC inhibitor ameliorates behavioral deficits in Mecp2(308/y) mouse model of Rett syndrome.

High Resolution Episcopic Microscopy for Qualitative and Quantitative Data in Phenotyping Altered Embryos and Adult Mice Using the New "Histo3D" System.

Importing genetically altered animals: ensuring quality.

INFRAFRONTIER quality principles in systemic phenotyping.

Integrative approach to interpret DYRK1A variants, leading to a frequent neurodevelopmental disorder.

Introduction to mammalian genome special issue: the microbiome in human health and disease.

Microglia-specific knock-down of Bmal1 improves memory and protects mice from high fat diet-induced obesity.

Multi-influential genetic interactions alter behaviour and cognition through six main biological cascades in Down syndrome mouse models.

Pathogenesis of Anorectal Malformations in Retinoic Acid Receptor Knockout Mice Studied by HREM.

Reliable and robust droplet digital PCR (ddPCR) and RT-ddPCR protocols for mouse studies.

SCA7 Mouse Cerebellar Pathology Reveals Preferential Downregulation of Key Purkinje Cell-Identity Genes and Shared Disease Signature with SCA1 and SCA2.

Targeting the RHOA pathway improves learning and memory in adult Kctd13 and 16p11.2 deletion mouse models.