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About ICS

A conditional null allele of Dync1h1 enables targeted analyses of dynein roles in neuronal length sensing.

Di Pizio A, Marvaldi L, Birling MC, Okladnikov N, Dupuis L, Fainzilber M, Rishal I
J Cell Sci 2023 Mar 1;136(5):

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A human dynein heavy chain mutation impacts cortical progenitor cells causing developmental defects, reduced brain size and altered brain architecture.

Romero DM, Zaidi D, Cifuentes-Diaz C, Maillard C, Grannec G, Selloum M, Birling MC, Bahi-Buisson N, Francis F
Neurobiol Dis 2023 May;180():106085

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A systematic review of the development and application of home cage monitoring in laboratory mice and rats.

Kahnau P, Mieske P, Wilzopolski J, Kalliokoski O, Mandillo S, Hölter SM, Voikar V, Amfim A, Badurek S, Bartelik A, Caruso A, Čater M, Ey E, Golini E, Jaap A, Hrncic D, Kiryk A, Lang B, Loncarevic-Vasiljkovic N, Meziane H, Radzevičienė A, Rivalan M, Scattoni ML, Torquet N, Trifkovic J, Ulfhake B, Thöne-Reineke C, Diederich K, Lewejohann L, Hohlbaum K
Bmc Biol 2023 Nov 13;21(1):256

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Changes in social behavior with MAPK2 and KCTD13/CUL3 pathways alterations in two new outbred rat models for the 16p11.2 syndromes with autism spectrum disorders.

Martin Lorenzo S, Muniz Moreno MDM, Atas H, Pellen M, Nalesso V, Raffelsberger W, Prevost G, Lindner L, Birling MC, Menoret S, Tesson L, Negroni L, Concordet JP, Anegon I, Herault Y
Front Neurosci 2023 ;17():1148683

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Comprehensive ECG reference intervals in C57BL/6N substrains provide a generalizable guide for cardiac electrophysiology studies in mice.

Oestereicher MA, Wotton JM, Ayabe S, Bou About G, Cheng TK, Choi JH, Clary D, Dew EM, Elfertak L, Guimond A, Haseli Mashhadi H, Heaney JD, Kelsey L, Keskivali-Bond P, Lopez Gomez F, Marschall S, McFarland M, Meziane H, Munoz Fuentes V, Nam KH, Nichtová Z, Pimm D, Bower L, Prochazka J, Rozman J, Santos L, Stewart M, Tanaka N, Ward CS, Willett AME, Wilson R, Braun RE, Dickinson ME, Flenniken AM, Herault Y, Lloyd KCK, Mallon AM, McKerlie C, Murray SA, Nutter LMJ, Sedlacek R, Seong JK, Sorg T, Tamura M, Wells S, Schneltzer E, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, White JK, Spielmann N
Mamm Genome 2023 Jun;34(2):180-199

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CRISMERE Chromosome Engineering in Mouse and Rat

Laurence Schaeffer, Loic Lindner, Guillaume Pavlovic, Yann Hérault & Marie-Christine Birling
Methods Mol Biol. 2023 31/03/2023;2631():277-297

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Development of HPV16 mouse and dog models for more accurate prediction of human vaccine efficacy.

Totain E, Lindner L, Martin N, Misseri Y, Iché A, Birling MC, Sorg T, Herault Y, Bousquet-Melou A, Bouillé P, Duthoit C, Pavlovic G, Boullier S
Lab Anim Res 2023 Jun 12;39(1):14

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Dissecting the autism-associated 16p11.2 locus identifies multiple drivers in neuroanatomical phenotypes and unveils a male-specific role for the major vault protein.

Kretz PF, Wagner C, Mikhaleva A, Montillot C, Hugel S, Morella I, Kannan M, Fischer MC, Milhau M, Yalcin I, Brambilla R, Selloum M, Herault Y, Reymond A, Collins SC, Yalcin B
Genome Biol 2023 Nov 15;24(1):261

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Genome-wide screening reveals the genetic basis of mammalian embryonic eye development.

Chee JM, Lanoue L, Clary D, Higgins K, Bower L, Flenniken A, Guo R, Adams DJ, Bosch F, Braun RE, Brown SDM, Chin HG, Dickinson ME, Hsu CW, Dobbie M, Gao X, Galande S, Grobler A, Heaney JD, Herault Y, de Angelis MH, Mammano F, Nutter LMJ, Parkinson H, Qin C, Shiroishi T, Sedlacek R, Seong JK, Xu Y, Brooks B, McKerlie C, Lloyd KCK, Westerberg H, Moshiri A
Bmc Biol 2023 Feb 3;21(1):22

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How much do we know about the function of mammalian genes?

Teboul L, Hérault Y, Wells S, Pavlovic G
Bmc Biol 2023 Dec 29;21(1):301

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IL-3 produced by T cells is crucial for basophil extravasation in hapten-induced allergic contact dermatitis.

Hachem CE, Marschall P, Hener P, Karnam A, Bonam SR, Meyer P, Flatter E, Birling MC, Bayry J, Li M
Front Immunol 2023 ;14():1151468

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Increased On-Target Rate and Risk of Concatemerization after CRISPR-Enhanced Targeting in ES Cells

Valérie Erbs, Romain Lorentz, Benjamin Eisenman, Laurence Schaeffer, Laurence Luppi, Loic Lindner, Yann Hérault, Guillaume Pavlovic, ,Marie Wattenhofer-Donzé and Marie-Christine Birling
Genes 2023 03/02/2023;14(2023):401

INFRAFRONTIER: mouse model resources for modelling human diseases.

Ali Khan A, Valera Vazquez G, Gustems M, Matteoni R, Song F, Gormanns P, Fessele S, Raess M, Hrabĕ de Angelis M
Mamm Genome 2023 Sep;34(3):408-417

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Prolonged nicotine exposure reduces aversion to the drug in mice by altering nicotinic transmission in the interpeduncular nucleus.

Mondoloni S, Nguyen C, Vicq E, Ciscato M, Jehl J, Durand-de Cuttoli R, Torquet N, Tolu S, Pons S, Maskos U, Marti F, Faure P, Mourot A
Elife 2023 May 30;12():

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Timeline of Developmental Defects Generated upon Genetic Inhibition of the Retinoic Acid Receptor Signaling Pathway

Marius Teletin, Manuel Mark, Olivia Wendling, Nadège Vernet, Betty Féret, Muriel Klopfenstein, Yann Herault, Norbert B. Ghyselinck
Biomedicines 2023 ;1(11):198

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