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Featuring keynote presentations, this symposium will allow participants to discover the latest applications of transgenics and cell based models for the study of gene regulation and disease. Comprehensive lectures provide in-depth discussion on the fundamentals of ZFNs as well as innovative applications for targeted gene knockout, integration, and tagging. Geared towards scientists interested in learning about the technology, the symposium provides researchers at all levels with a unique opportunity for networking with peers. Discussions will facilitate the exchange of ideas to shape the future directions of research in this key area.