Services

Objectives

This training aims to provide a general framework to learn the basic knowledge and to get scientists start using phenotyping approaches for answering “What’s wrong with my mice”

• Understand the interest of phenotyping to characterize gene function in mouse models,
• Learn about the scientific and ethical considerations in phenotyping,
• Hear about the current web resources available,
• Learn good practices by experimentation (5 workshops) 

Audience

The training is opened to graduate students (PhD), post-doctoral scientists, researchers, and engineers.

Training Programme:

Courses (In the morning)

• Phenotyping or functional analysis: Cardiology, Behavior, Blood chemistry, Imaging, Metabolism, Neurobiology, Pathology.
• Evaluation of the embryonic lethality: first strategy.
• Experimental design: Basic notions in Mutagenesis, Statistics, Ethics and legislation.
• The large research consortia and Data banks

5 Workshops: What’s wrong with my mice? (In the afternoon)

• Behavior phenotyping: first approaches (Shirpa, Rotarod and Openfield)
• Applications of echography to cardiac and embryo phenotyping
• Blood sampling demonstration
• Anatomo-pathology: the necropsy as the crucial and complementary step to the in vivo studies
• Dissection of Embryos in perinatal developmental step.

Interactive Discussion Groups (at the end)

This session consists of open-ended questions in order to allow each attendee to consider their own scientific issue.

REGISTRATION AND MORE INFORMATION:

https://cnrsformation.cnrs.fr/stage-17232-Mouse-model-for-diseases-approaches-for-phenotyping.html?mc=mouse