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    al onCERBM logottp: li2net 20 View on PubMed<0c/img/pubmed-icon.pnglogosglogo-igbmc-footer-w
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    2017


    A Fast, Easy, and Customizable Eight-Color Flow Cytometric Method for Analysis of the Cellular Content of Bronchoalveolar Lavage Fluid in the Mouse.

    Daubeuf F(1)(2), Becker J(3), Aguilar-Pimentel JA(4), Ebel C(5), Hrabe de Angelis M(4), Herault Y(3)(5)(6)(7)(8), Frossard N(1)(2).
    Curr Protoc Mouse Biol 2017 Jun 19;7(2):88-99

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    A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.

    Bowl MR(1), Simon MM(1), Ingham NJ(2)(3), Greenaway S(1), Santos L(1), Cater H(1), Taylor S(1), Mason J(4), Kurbatova N(4), Pearson S(3), Bower LR(5), Clary DA(5), Meziane H(6), Reilly P(6), Minowa O(7), Kelsey L(8)(9)(10); International Mouse Phenotyping Consortium, Tocchini-Valentini GP(11), Gao X(12), Bradley A(3), Skarnes WC(3), Moore M(13), Beaudet AL(14), Justice MJ(8)(9)(10)(14), Seavitt J(14), Dickinson ME(15), Wurst W(16), de Angelis MH(17), Herault Y(6)(18)(19)(20), Wakana S(7), Nutter LMJ(8)(9)(10), Flenniken AM(8)(9)(10), McKerlie C(8)(9)(10), Murray SA(21), Svenson KL(21), Braun RE(21), West DB(22), Lloyd KCK(5), Adams DJ(3), White J(3), Karp N(3), Flicek P(4), Smedley D(23), Meehan TF(4), Parkinson HE(4), Teboul LM(1), Wells S(1), Steel KP(2)(3), Mallon AM(1), Brown SDM(24).
    Nat Commun 2017 Oct 12;8(1):886

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    Atp6ap2 ablation in adult mice impairs viability through multiple organ deficiencies.

    Wendling O(1), Champy MF(1), Jaubert S(2), Pavlovic G(1), Dubos A(1)(3)(4)(5)(6), Lindner L(1), Jacobs H(1), Mark M(1)(3)(4)(5)(6), Combe R(1), Da Cruz IG(1), Luche H(6), Mudgett JS(7), Rosahl T(7), Sorg T(1), Malissen M(2), Reilly PT(1), Herault Y(8)(9)(10)(11)(12).
    Sci Rep 2017 Aug 29;7(1):9618

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    Comparing ataxias with oculomotor apraxia: a multimodal study of AOA1, AOA2 and AT focusing on video-oculography and alpha-fetoprotein.

    Mariani LL(1)(2), Rivaud-Pechoux S(3), Charles P(1), Ewenczyk C(1), Meneret A(2)(3), Monga BB(4), Fleury MC(5)(6)(7), Hainque E(8)(9)(10), Maisonobe T(11), Degos B(2), Echaniz-Laguna A(5)(12), Renaud M(5)(6)(7), Wirth T(5), Grabli D(2)(9), Brice A(1)(9)(10), Vidailhet M(2)(9)(10), Stoppa-Lyonnet D(13)(14), Dubois-d'Enghien C(13), Le Ber I(2)(9), Koenig M(15), Roze E(2)(9)(10), Tranchant C(5)(6)(7), Durr A(1)(9)(10), Gaymard B(16), Anheim M(17)(18)(19)(20).
    Sci Rep 2017 Nov 10;7(1):15284

    View on PubMed

    De Novo Mutations in Protein Kinase Genes CAMK2A and CAMK2B Cause Intellectual Disability.

    Kury S(1), van Woerden GM(2), Besnard T(3), Proietti Onori M(2), Latypova X(3), Towne MC(4), Cho MT(5), Prescott TE(6), Ploeg MA(2), Sanders S(7), Stessman HAF(8), Pujol A(9), Distel B(10), Robak LA(11), Bernstein JA(12), Denomme-Pichon AS(13), Lesca G(14), Sellars EA(15), Berg J(16), Carre W(17), Busk L(6), van Bon BWM(18), Waugh JL(19), Deardorff M(20), Hoganson GE(21), Bosanko KB(15), Johnson DS(22), Dabir T(23), Holla L(6), Sarkar A(24), Tveten K(6), de Bellescize J(25), Braathen GJ(6), Terhal PA(26), Grange DK(27), van Haeringen A(28), Lam C(29), Mirzaa G(30), Burton J(21), Bhoj EJ(31), Douglas J(32), Santani AB(33), Nesbitt AI(34), Helbig KL(35), Andrews MV(27), Begtrup A(5), Tang S(36), van Gassen KLI(26), Juusola J(5), Foss K(37), Enns GM(12), Moog U(38), Hinderhofer K(38), Paramasivam N(39), Lincoln S(32), Kusako BH(32), Lindenbaum P(40), Charpentier E(40), Nowak CB(32), Cherot E(17), Simonet T(25), Ruivenkamp CAL(28), Hahn S(29), Brownstein CA(4), Xia F(41), Schmitt S(3), Deb W(3), Bonneau D(13), Nizon M(3), Quinquis D(3), Chelly J(42), Rudolf G(43), Sanlaville D(14), Parent P(44), Gilbert-Dussardier B(45), Toutain A(46), Sutton VR(47), Thies J(48), Peart-Vissers LELM(18), Boisseau P(3), Vincent M(3), Grabrucker AM(49), Dubourg C(17); Undiagnosed Diseases Network, Tan WH(32), Verbeek NE(26), Granzow M(38), Santen GWE(28), Shendure J(50), Isidor B(3), Pasquier L(51), Redon R(40), Yang Y(41), State MW(7), Kleefstra T(18), Cogne B(3); GEM HUGO(52); Deciphering Developmental Disorders Study(53), Petrovski S(54), Retterer K(5), Eichler EE(50), Rosenfeld JA(11), Agrawal PB(55), Bezieau S(56), Odent S(51), Elgersma Y(57), Mercier S(3).
    Am J Hum Genet 2017 Nov 2;101(5):768-788

    View on PubMed

    Deciphering the Role of Oncogenic MITFE318K in Senescence Delay and Melanoma Progression.

    Bonet C(1)(2), Luciani F(3)(4), Ottavi JF(1)(2), Leclerc J(1)(2), Jouenne FM(5), Boncompagni M(1)(2), Bille K(1)(2), Hofman V(2)(6), Bossis G(7), Marco de Donatis G(8), Strub T(9), Cheli Y(1)(2), Ohanna M(1)(2), Luciano F(10), Marchetti S(10), Rocchi S(1)(2), Birling MC(1)(11), Avril MF(12), Poulalhon N(13), Luc T(13), Bertolotto C(1)(2).
    J Natl Cancer Inst 2017 Aug 1;109(8):djw340

    View on PubMed

    Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium.

    Meehan TF(1), Conte N(1), West DB(2), Jacobsen JO(3), Mason J(1), Warren J(1), Chen CK(1), Tudose I(1), Relac M(1), Matthews P(1), Karp N(4), Santos L(5), Fiegel T(5), Ring N(5), Westerberg H(5), Greenaway S(5), Sneddon D(5), Morgan H(5), Codner GF(5), Stewart ME(5), Brown J(5), Horner N(5); International Mouse Phenotyping Consortium, Haendel M(6), Washington N(7), Mungall CJ(7), Reynolds CL(8), Gallegos J(8), Gailus-Durner V(9), Sorg T(10)(11)(12)(13), Pavlovic G(10)(11)(12)(13), Bower LR(14), Moore M(15), Morse I(16), Gao X(17), Tocchini-Valentini GP(18), Obata Y(19), Cho SY(20)(21), Seong JK(20)(22), Seavitt J(8), Beaudet AL(8), Dickinson ME(8), Herault Y(10)(11)(12)(13), Wurst W(9), de Angelis MH(9), Lloyd KCK(14), Flenniken AM(23), Nutter LMJ(23), Newbigging S(23), McKerlie C(23), Justice MJ(24), Murray SA(25), Svenson KL(25), Braun RE(25), White JK(4), Bradley A(4), Flicek P(1), Wells S(5), Skarnes WC(4), Adams DJ(4), Parkinson H(1), Mallon AM(5), Brown SDM(5), Smedley D(3).
    Nat Genet 2017 Aug;49(8):1231-1238

    View on PubMed

    Dry ice is a reliable substrate for the distribution of frozen mouse spermatozoa: A multi-centric study.

    Raspa M(1), Guan M(2), Paoletti R(3), Montoliu L(4), Ayadi A(5), Marschall S(6); EMMA/Infrafrontier Technical Working Group, Fray M(2), Scavizzi F(7).
    Theriogenology 2017 Jul 1;96():49-57

    View on PubMed

    Efficient and rapid generation of large genomic variants in rats and mice using CRISMERE.

    Birling MC(1), Schaeffer L(1), Andre P(1), Lindner L(1), Marechal D(1), Ayadi A(1), Sorg T(1), Pavlovic G(1), Herault Y(1,)(2,)(3,)(4,)(5).
    Sci Rep 2017 Mar 7;7():43331

    View on PubMed

    Fluorescent nanodiamond tracking reveals intraneuronal transport abnormalities induced by brain-disease-related genetic risk factors.

    Haziza S(1,)(2), Mohan N(1), Loe-Mie Y(2), Lepagnol-Bestel AM(2), Massou S(1), Adam MP(1), Le XL(1), Viard J(2), Plancon C(3), Daudin R(2), Koebel P(4), Dorard E(2), Rose C(2), Hsieh FJ(5), Wu CC(6), Potier B(2), Herault Y(4), Sala C(7), Corvin A(8), Allinquant B(2), Chang HC(5), Treussart F(1), Simonneau M(1,)(2,)(9).
    Nat Nanotechnol 2017 May;12(4):322-328

    View on PubMed

    Modeling human disease in rodents by CRISPR/Cas9 genome editing.

    Birling MC(1), Herault Y(2)(3)(4)(5)(6), Pavlovic G(2).
    Mamm Genome 2017 Jul 4

    View on PubMed

    Mouse models of 17q21.31 microdeletion and microduplication syndromes highlight the importance of Kansl1 for cognition.

    Arbogast T(1)(2)(3)(4), Iacono G(5), Chevalier C(1)(2)(3)(4), Afinowi NO(6), Houbaert X(7), van Eede MC(8), Laliberte C(8), Birling MC(9), Linda K(10), Meziane H(9), Selloum M(9), Sorg T(9), Nadif Kasri N(10), Koolen DA(10), Stunnenberg HG(5), Henkelman RM(8), Kopanitsa M(6), Humeau Y(7), De Vries BBA(10), Herault Y(1)(2)(3)(4)(9).
    Plos Genet 2017 Jul 13;13(7):e1006886

    View on PubMed

    Non-invasive quantitative imaging of hepatocellular carcinoma growth in mice by micro-CT using liver-targeted iodinated nano-emulsions.

    Anton N(1)(2), Parlog A(3)(4)(5)(6), Bou About G(3)(4)(5)(6), Attia MF(7)(8)(9)(10), Wattenhofer-Donze M(3)(4)(5)(6), Jacobs H(3)(4)(5)(6), Goncalves I(3)(4)(5)(6), Robinet E(11), Sorg T(3)(4)(5)(6), Vandamme TF(7)(8).
    Sci Rep 2017 Oct 24;7(1):13935

    View on PubMed

    Nox4 genetic inhibition in experimental hypertension and metabolic syndrome.

    Bouabout G(1), Ayme-Dietrich E(2), Jacob H(1), Champy MF(1), Birling MC(1), Pavlovic G(1), Madeira L(2), Fertak LE(1), Petit-Demouliere B(1), Sorg T(1), Herault Y(1), Mudgett J(3), Monassier L(4).
    Arch Cardiovasc Dis 2017 Nov 4

    View on PubMed

    Prevalence of sexual dimorphism in mammalian phenotypic traits.

    Karp NA(1)(2), Mason J(3), Beaudet AL(4), Benjamini Y(5), Bower L(6), Braun RE(7), Brown SDM(8), Chesler EJ(7), Dickinson ME(9), Flenniken AM(10), Fuchs H(11), Angelis MH(11)(12)(13), Gao X(14), Guo S(14), Greenaway S(8), Heller R(5), Herault Y(15)(16)(17)(18)(19), Justice MJ(20), Kurbatova N(5), Lelliott CJ(21), Lloyd KCK(6), Mallon AM(8), Mank JE(22), Masuya H(23), McKerlie C(10)(24), Meehan TF(3), Mott RF(25), Murray SA(7), Parkinson H(3), Ramirez-Solis R(21), Santos L(8), Seavitt JR(4), Smedley D(26), Sorg T(15)(16)(17)(18)(19), Speak AO(21), Steel KP(21)(27), Svenson KL(7); International Mouse Phenotyping Consortium, Wakana S(23), West D(28), Wells S(8), Westerberg H(8), Yaacoby S(5), White JK(7)(21).
    Nat Commun 2017 Jun 26;8():15475

    View on PubMed

    Ptchd1 deficiency induces excitatory synaptic and cognitive dysfunctions in mouse.

    Ung DC(1,)(2), Iacono G(3), Meziane H(4), Blanchard E(1,)(5,)(6), Papon MA(1,)(2), Selten M(7), van Rhijn JR(7), Montjean R(8,)(9,)(10,)(11), Rucci J(8,)(9,)(10,)(11), Martin S(12), Fleet A(13), Birling MC(4), Marouillat S(1,)(2), Roepman R(14,)(15), Selloum M(4), Lux A(4), Thepault RA(1,)(2), Hamel P(13), Mittal K(16), Vincent JB(16), Dorseuil O(8,)(9,)(10,)(11), Stunnenberg HG(3), Billuart P(8,)(9,)(10,)(11), Nadif Kasri N(7,)(14), Herault Y(4,)(17,)(18,)(19,)(20), Laumonnier F(1,)(2,)(6).
    Mol Psychiatry 2017 Apr 18

    View on PubMed

    RF313, an orally bioavailable neuropeptide FF receptor antagonist, opposes effects of RF-amide-related peptide-3 and opioid-induced hyperalgesia in rodents.

    Elhabazi K(1), Humbert JP(2), Bertin I(3), Quillet R(4), Utard V(5), Schneider S(6), Schmitt M(7), Bourguignon JJ(8), Laboureyras E(9), Ben Boujema M(10), Simonnet G(11), Ancel C(12), Simonneaux V(13), Beltramo M(14), Bucher B(15), Sorg T(16), Meziane H(17), Schneider E(18), Petit-Demouliere B(19), Ilien B(20), Bihel F(21), Simonin F(22).
    Neuropharmacology 2017 May 15;118():188-198

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    Rodent models in Down syndrome research: impact and future opportunities.

    Herault Y(1)(2)(3)(4)(5), Delabar JM(5)(6)(7)(8), Fisher EMC(5)(9)(10), Tybulewicz VLJ(5)(10)(11)(12), Yu E(5)(13)(14), Brault V(15)(2)(3)(4).
    Dis Model Mech 2017 Oct 1;10(10):1165-1186

    View on PubMed

    Synaptic dysfunction in amygdala in intellectual disorder models.

    Aincy M(1), Meziane H(2), Herault Y(3), Humeau Y(4).
    Prog Neuropsychopharmacol Biol Psychiatry 2017 Jul 31

    View on PubMed

    Translation of Expanded CGG Repeats into FMRpolyG Is Pathogenic and May Contribute to Fragile X Tremor Ataxia Syndrome.

    Sellier C(1), Buijsen RA(2), He F(3), Natla S(4), Jung L(5), Tropel P(5), Gaucherot A(5), Jacobs H(6), Meziane H(6), Vincent A(5), Champy MF(6), Sorg T(6), Pavlovic G(6), Wattenhofer-Donze M(6), Birling MC(6), Oulad-Abdelghani M(5), Eberling P(5), Ruffenach F(5), Joint M(5), Anheim M(7), Martinez-Cerdeno V(8), Tassone F(9), Willemsen R(2), Hukema RK(2), Viville S(10), Martinat C(11), Todd PK(12), Charlet-Berguerand N(13).
    Neuron 2017 Jan 18;93(2):331-347

    View on PubMed

    2016


    Altered microtubule dynamics and vesicular transport in mouse and human MeCP2-deficient astrocytes.

    Delepine C(1), Meziane H(2), Nectoux J(3), Opitz M(1), Smith AB(4), Ballatore C(5), Saillour Y(1), Bennaceur-Griscelli A(6), Chang Q(7), Williams EC(7), Dahan M(8), Duboin A(9), Billuart P(1), Herault Y(2), Bienvenu T(10).
    Hum Mol Genet 2016 Jan 1;25(1):146-57

    View on PubMed

    Aneuploidy screening of embryonic stem cell clones by metaphase karyotyping and d ta-eon">

    4etape8en/ue E(8)(gt; fonenu T(10)ea

    Bowl MR(1), Simtewart ME(), Marechal D(gueraven> A), Chen M(6), BirlingéT(1), Heade MoA2), NecrAB(Natla Eia Rienn(5), TrMouxnéT(3), DEve a EPGriscel10(e FrVGriscizzi F), Sor Oulad-Abdel), Viénvenu T(10).Wattenhofer, Cholls S(1Prog NeuropsychBmcnt of19;7(2):86jw340 3

    View on PubMed

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    Bouabout G(1), Lez Mr9).ng PHeFith g Q(7L, Soryr D,AMighanvacca(E),Bourl A,)DeutsM(5S PetkibASeatai-ceya(6ops S-DurA Bienvenu T7), Mo), Sns LA(eenaigoll SParloarak017SENat Commun 2017 Jues.<):86j17;531(7594):40

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    Aneuploidy screCouuse ct/">Re in betwextethymones mE(8gt;pl P2), in-

    IL-23-dr), Huremu Thax kashap kask disoflypice in intT usi apraiandlti-l (8)weighcyte-reBouabout G(1), Li1), TudLeyva-Cang" lo, Fi), Biehal C(1), Mia Rienn(A2), NZaa i G(1), J)(5) , van L(6G(1)(11), Avril MBertoi, TheJ Natl Cancer InsAult g Frlt R(emu 7(2):86j ;138p> 0-16

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    Rodent models iDYRK1A Batesse M-Sbolins in1;25 Involve

    18;9dsorders Study(53), PetPasqBatTView Dru Disorders Stme resear

    Sellier C(1), BDuesca A2), Bienvenu T(10J Natl Cancer IFal Wcelhav> 18;9sci2):86j n 386 View on PubMed

    Ptchd1 deficienE4F1- nd onu" r7(2atepyruvtribdehy Hum Mol Genet 2P st 201Acad t 24U S A2):86jS7(1)7;113(32):11004-

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    Ptchd1 deficienEandlti-l-i> ifin aroduplicateCD44ensive une gdala in intke genn

    4> eandnsTremome(5)(1c1, AO Sellier C(1), BuhgenChahvili(4), BaBurkG(142iscizznz CM(51), RceL(2), FKang" RF(224).

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    A large scale hFasudiormaeaps Stme rirs vinsiv> behavi 1, (5)(ggies in moenarians Stme rOligopw.nic -1n MeCP2 from atesorder models.Kury S(1), van Schneider E, FKhry-aoui 1), Adaourllo,4), Sm8)ba C(5),Calc(2),emois R(eibel-FincentWC(4), Ax A(4), T Tudoself G(4, De Vries BBA(10Rieau M(1,)Za(6)9), Cheudgett J(3), M
    ), SGiuste/> M(8,)(9,)(10,)(11Hum Mol Genet 2016 Jan 1;25(1):146-u7

    2314-2323

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    Ptchd1 deficienT ofmg ConWnt/PCP

    lVnnal2 is id SonneR(utiomig genomiatefarchlrbrdinhioa multort abs,irtungdala in> d,pend StlpllarD(10)vder dMeehan TF(1), C on"co D4), Balleyar21anehV FBryiStmWPaFritzorh(BWuSer nun,AgPaudyaA1)(6Brown J(5hePadanoP8)Cad Be MaRhais-N tonGHeYa MW(1,) -AbdRTrMurdHcorJN),Cotd>r ankhasSPCurr Protoc MouDev 9;7(2):82 Sep98211-22

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    Rodenr/> 1

    A Fast, Easy, awencacterizgenomirtunVd dtrnomiateCre-Drivg 1Pg ConLsee eehan TF(1), C offloC(F8), impy MF(acCencto), n FBulad-AbdeChWa X VAuwerxALurr Protoc Mousurr.lPr oc.(Pg Con9;7(.2):81), Ro,2):81;1(p>1-1

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    Nox4 genetic inCr tribTaeaps Stm apraalPr m25si nunGABA-A 5-Ser monverInvg ConAgz-n n Ioraeatws Imm nd Earlt 1;25s Exp

    durd-Abdemory L)vdes/h4>anesear

    32

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    Rodent models iGrge23cirtunplati-ct/">sc1, evalu ls/h4>an MeCP2 from laristhm Bouabout G(1), D kcoaap 1K VC 81-

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    Disease model dInvolves Stm Corstitol)),hyd C(2 an 10/h4>(uzry tribpe M(rnse imtiorescuMITFEits eals spedala in byfmase Phlenstityp),hydd taeaps StHerault Y(1)(2)(an nbd FSMAuhbavr(BW Nieror ekthviMKa DolléMPCurr Protoc Mou st 201Acad t 24U S A2):81935 View on PubMed

    Nox4 genetic inPg Con9reedse imtioiolony)Maiages Stincy M(1), Mezi2T(1),Ageti>mtio)),Gonc1,vgieduche H(6ChWa Xurr Protoc Mousurr.lPr oc.(Pg Con9;7(.2):81), Ro,2):81;1(p>t39?26

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    Ptchd1 deficienPTBP1pIs,Requi dynutioEuzry tribDsorders St befe I(Gistr">Re innton N(1)(2), guckil>(J.8), impy MF(., (5njkvr(J.8)JamviMM., (unnger C.Hernaed-ssiT(1s1K., Brown J(A.F., BolEbelabdMol Psychiatry PJul On.<):81 ;6

    e16992

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    Ptchd1 deficienRediseaseody weight h4>Til>(Tspan8-dstes. StmT usDelepine C(1), Crling MC ELe Mo 24R FSx A(4), , Water LR(LBW Cumisk y(228)hlom ENat Genet 2017 Irt605-1

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    A large scale h),and017 zeasPost-Mortem Examp>genomirtunFixgenomi des.arutioMteiStm tunTaeapeasPbatincy M(1), MeziStudyd.C.HemuIn.y<):81 ;1(p>1-3

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    Translation of TASK-3 5sea potsotiaennntsd7( iStm>View Meehan TF(1), C autnsoALSeavitarg Q(7VC)(LoritsSM S GaHenka4),PLChKraus,RL Fh Fahl TWntSchneider),MootiaenMMiRenceoDRCo snviMKa McClinbx A1)(6Bronter Jraur, Her(JI23Fox SV);U,z t PV FBaylnceoDA1).inrow CJraReWansoJJProg NeuropsychBlate Res2):8193569-7

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    Translation of Thd trdemigg0tpeetnlteo oficientcr mosomeF21mu m CstbitovPrmt2 is i id SonneR(utioo ofgoc26 multso ofTc1n MeCP2 from laresearch: impaellier C(1), BDuesca A. UPoth3ghl .)((3)(4).<.), hasonA.J.8)Tybulewicz.<.L.br)(10), T.M., ienvenu TNat Genet 2017 Behav Blate Res2):819271-8

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    A large scale hTIF1bme.1a MPc n m apraHP1 iomesssotiaenu" apost-gistr">Re inidsorders St,sbut tiunu" aSert h4nmetapgdala in> durd-Absp ti-t9arge deerault Y(1)(2)(erzogMM., , impy MF(., G, Roou F., Crlibis P.7)(5)(6)C,nLssuca G., CapicsRFSci Rep 2017 OcDev 9;7(2):81jFeb><5;350

    548-5

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    A larr/> 0

    A Fast, Easy, anmonvermuItilaye dyncapsul.arutiote varo(bo Thfced e innton N(1)(2), Faccal .)(Cortez C.HeM imoza-Pademas.arC.HeM adeq C.ChDeigg0(1).8)Johnngca A.P.7)(5p>grd ENunVoeg EJ.C.HeCaruso F., Benkirite-JecenloNCurr Protoc Mou st 201Acad t 24U S A2):80jFeb>23;107/8p>3406-1

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    Translation of Aule dynh4po

    lome.1349-6>

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    Disease model dbme.-Endilian exp

    /h4>o of MeCP2rctityury S(1), van Goflagh.3130-4

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    Ptchd1 deficienragile X plicatearge-.31ifi inmbatDrtunsing tov vr(usser ,andllulateo ofc017 ovas in moplati-ct/">y ouabout G(1), Mer/> M8)LapubM <(P.).8)i2T(1)T.a DolR(5. Via View on PubMed

    Rodent models iesear

    :aFr m Usser ,andllulo of 18;9boyl">y14943-1494

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    A large scale hEuse ovirus-re and oa m apraacX Trmyoc017 tieBouabout G(1), V StéoPLChBuulaet1TChRenoi> View on PubMed

    Ptchd1 deficienE8;9Ph4:vaore dsiGory utiohigh-thrrganputm MeCP2portium, Wakdutaouabout G(1), Meer GF(.8)uila)T.a Blake),.(6Ga

    4H.HerkinsoC.ChDlls zy G. FLeb5,)(IS.8)Lenggg 1A.,)Mai S(1., (ilquanD.)(2chneiderP GRi(6), ankoD.Chterberg.An.
    .An.ood> .An), Lloyd KCK.H.8)hesler .D.ChHdin c KJ.M., Mak JE(2.1Sci Rep 2017 Oc uclein AcigosRes2):80 Jan;38(Dutadap> nceue):D577-8

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    Ptchd1 deficienIDowntfes highlrodarge Drtunnetworks danv Wakc017 ovas in moyndrome.

    ts.p>2h4>an MeCP2f2fiuse cr ssouabout G(1), D ne J.M., Zh -Ab1., (olony)A.,)Macneil D., G,he hakure.1D., Zha MWB. Baudg(t M8)Vogt)T.a Cu,ly(D., Kasarsk017)., B(6)dteE.EMol Psychiatry PJul On.<):80 ;5(1/p>e1431

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    Aneuploidy screMurd-eanAmsatudyinfela in p ovide Drt ,ffds. St2 from utioconargieudyo in motoxopubsmo deerault Y(1)(2)LahmasiI.eenai>grd . VSaunsoA. Via metah4> M8)Abromrahman)T.a Roux P.,)190-

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    2016

    lama1 disrupsenstitypivas in modsorders Stmatioi Her(limit Wakm(uzra Thfced e innton N(1)(2), Edw), a P.M., Mammadova-BaH(1)M8)Alng F., K Cinl). B8)ckl W.L.brRoux P.,)gham -AssmantsP.MullatheR.g.AnOrend G. FWu02 View on PubMed

    Translation of Myrderr/h4fe genvernAmpubsm disease-r="h09i> nverexp

    /rodJAK2V617Flintknock- n T usDelepine C(1), leetynCezL-ctut1A,)Ma yt R) BHysitsS(6ziaquo), , Bulad-AbdeChVainH(enk.):80jw3405;116>5p>783-

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    Aneuploidy screNeggenvernu" r7(/rodSm/ oa /Tif1gammaepe M(rnsst ofmapic trai(uzry ouabout G(1), Meesut1LNHeYanfK.P.MuEnzo1)M8)Aragz-a P.,)g/h4gor .M., , impy MF(., (5)(6)C,nKh tgh(4)ianfK.8)he iS G. FCrlibis P.7)DundntIS.8)Lssuca G., Piccolo,rSci Rep 2017 OcDevrders Stm):80jw340<;137(15p>2571-

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    Aneuploidy screOx dtrnv21dis

    lskroduudymusct P09imu ands earlt exp

    /rodRad/h4>an MeCP2 from larimyot;9plriblase ypisct ;9sieBouabout G(1), HJule B),Gonzalezn), LguiiannJLChRene0F,)Pcob , , Frilar-P(eeEaaa tz-Laguna1)(6DunuiC L, Larome T7)Lo,ffn. View on PubMed

    Aneuploidy screPCSK9 is i involve

    o ofdegradtrnomiateLDLonist, op>katioBACE1/h4>o ofirs vin MeCP2blateBouabout G(1), LiunM FWugeti CVMol Psychiatry J1LipidsRes2):80 Sep;51a M:2611-

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    A large scale hRstito3circid)nist, opp(RAR)-alpha is i critsc1,lym equi dynutiom ny MFrstito3circid)eff.-relh4>o ofdevrder WakmMeCP2rctityury S(1), van CapicsRLNHeTrensz F., J n li ,.(6Ghyseaseck N.B.7)Roux P.J.8)DolleMPCurr Protoc MouInvgst Ophthalm7(2V017Sci2):80200n;51(6 3281-9>

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    A large scale hThd pollteiStmdiethylhexyl phthal nd ct/">Rees2hepap4> rge gylome. ies-i> ifin PPARalpha-),pend Stmmeaaa t m>Herault Y(1)(2)FeigerJN),GacobyeAMiCysils-Cysi iC27Ya MWQ1).inklviMC Foedu(E),Buenof , Gelman)L VAuwerxAL)(GonzaleznFC(6)(sve gne0BMol Psychiatry Envirca HeJulh Wari> t2):80jFebi118

    2 4-4

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    Transr/> 09

    A Fast, Easy, andruo onium-nu" lluleer Goome.lh4> compound ctdisesstumultgrowlh thrrgan dishighlrodo of imopubsm4> rcti inum1dis View on PubMed

    Translation of Blate s ucu p>2hmp e

    o offour-p and tgst P(nanv21td> experiK(cMd SwnceombatDu o of5-HT2Apagz-n n DOIHerault Y(1)(2)P R(19), Ilieè(1),eeSn">é C Ewrgreln FHn"coëy 28)h), inMCMol Psychiatry Behav Blate Res2):09 elo 200-

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    Nox4 genetic inEffds. St2tensl1u,ly-nu" r7(lMd tView inmteiarge de

    lsmoopramusct Pmeta>lrodo ofirs vimMeCPerault Y(1)(2), impy MF(., Bo T(1t J.M., Crlibis P.7)(etzmviMnNeuron 2017 Jan1;25si>14-

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    Translation of IDowntfes highlrodo ofUBP1plocu> 5sea critsc1, blood>p es.She,u genomi Cot17q21td> icientgrge23c>Herault Y(1)(2)Moutnikova H, Laaksof , Lu)L VCruz IGa PaananetsL)(Kuuubsmaa1TChKuusisaosL)(Härd-AbHUAnHyouetsT,)Pcser etsOMullatheUAnHyoefawalM FWilh4insoRW VAuwerxALNat Genet 2017 Jul 13;13(7)09 Aug;5/8p>e614059

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    Disease model dPpVieapic2 is a k y(drivg 1 Colonarvtiplh4>o of MeCPincy M(1), MezirgmantsC.8)Dob inMR., ieikkh gnoS.8)Aubu yt R).8)P),i,lymL.)(Cola)T.).8)Moutnikova H. VZhue1140752

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    Translation of Site-i> ifin nisombp>gs.arutiomanip">Re inirodo oft17q21s in tincy M(1), Mezhulad-Abd.C.He offloC(F.ChWa XNat Genet 2017 7ethod iJan 9;7(2):09 ;561(p>t45-63

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    A large scale hThd Hisao ThDeacetylap> SIRT1 Cu" r7(s Makegetitiltiplh4>PbatDThrrgan Rt/">Re inirodHypothal mba-PituitneR(Gonadot;9ph4>Signaad-Aerault Y(1)(2)Molthur-Seethar21 UNHeTee, a K.7)RooijMnNG., , impy MF(., (cBg T(y . VSasucae-Corsi P.7)Davi ankoI.at Genet 2017 Biol ;7( od>):09 Febi80

    384-9

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    Nox4 genetic inThd Pro12Ala PPAReapic2 Vari nunD Bermp>4s)(et. 88-9

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    2016


    08

    A Fast, Easy, annxiolyico-like)eff.-rellareOIl1)cr Pjela ine

    aoso ofiippocansu> (but tiuno ofrimygdal tiioo ofPAG)lh4>o of batDfour p>Rees2tgstDelepine C(1), lecenbFChr R(19), Iliee(1),eeDuboi>291-

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    Ptchd1 deficienEvalu katioalii-l fromellarperiphe ypin18;9pachie>Herault Y(1)(2)Frilar-P(eeMuIn.72-10

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    Ptchd1 deficienFacetis2triggg 4s)eff.-relh4>o ofFour-P and Tgst--retgst P(T usDelepine C(1), P R(19), Ilieè(1),eeHn"coëy 28)h), inMCMol Psychiatry Evr( 18;9pJul 9plati-ct/2):08jJan;18p> 41-

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    2016

    4srome. ts.p>2h4>o of MeCPincy M(1), MezCrling M.F., Bx A(4), . VZeitn.318-3

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    Nox4 genetic inNocist, nn)nist, oppim oirs nisognie in memory via iuse acn m apraNMDA)nist, op-),pend Stmmit9arg-a lkp>gs./ext acx Ain mosignaa-ct/">Reedlkp>gs.osignaaeehan TF(1), C aeldng 1A.,)RenceoD.acoirhmantsL.)(2chneiderP GKieff.27;28a M:2190-

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    Disease model dReliabiltip, robust>4ss,irtunr7( oducibiltiplh4> MeCP2behavi ral2portium, Wa:ea cross-lc/">IGory studyelepine C(1), lend Roo(S.8)Tucci2V., ioule .M., 2chneiderP GBdinhac/"u GP P.).8)Kallnik6)C,nLaderPV., NoubMsP.CMbrouagazza S(.CM Ewrgh RoeE.m.eenakegK.He olt i1)M8)ziaquo), .ieKrezom W.8)ParknsoA. VRieau .ChB(6neit-DeI., (5)azzie oD.acAuwerxALN8)hesler .D.ChCrlibis P.7)Ros Fthaln .),Tni GP(18), Obata Y(. B ngelisNat Genet 2017 Physiol 4 View on PubMed

    A large scale hThd grge23c ab>Re inirodSRC-3 <-reltgateeliobestiplatioimp ovp>2h4sulte steri View on PubMed

    Ptchd1 deficienVari a in> DNA elisldand mole in monetworks that caeCP2dise anincy M(1), MezCren TN8)Zhuaos5. ViacNeil D.J., Zha MWCC,nLamb27;452(7186 429-3

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    Disear/> 07

    A Fast, Easy, an(1K(cMITFEdopamp>4)D2onist, op>kunmask Drt inhibieory nu" r7(/rver o ofblate circuitrie Dr View on PubMed

    2016

    ifin p>g l <-reltgateelidiabestiplbecaeCP2TFEioraeatworrge gylexpend 2es.elepine C(1), Mnad-YoisefoC.ChMatakiWCC,nCoste),.(6M addeq C.ChGiaoudl .)((5,)(IS.8)KoehlWCC,nCrling M.F., Crlibis P.7)FajcsRLNHe(etzmviMnN GSchoonjana K.7)AuwerxALNat Genet 2017 st 201Acad t 24U S A2):07)Ju 19;104(25p>10703-1070

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    Rodent, Easy, anlii-l fromellaranxieay h4>T usDelepine C(1), h), inMCChr R(19), Ilieè(1),eeDhoninhadha B FHn"cöet CMol Psychiatry Fundam Clt Plati-ct/<):07)eloi21(6 567-7

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    Aneuploidy screB e0Fced e in2 i hed e-rSyge gy-nmon MWGrowlh Facetis2Embedded/h4>anPolyer mo>glytndMuItilaye Filmelepine C(1), Meigg0(1).8)Le GuenME.(6M addeq C.ChStoulz J.FC,nNeutnsoP.8)B(6)afoP.8)Voeg EJ.C.HeBenkirite-JecenloNCurr Protoc MouAdva(cMd Mase ndlf):07);19(5p>693-9

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    Ptchd1 deficienEs us cyct Peff.-rellnsbehavi rr Co557BL/6JkatioBALB/cByJ>fenil>>T us: hmp in> u" aportium, Waks asegie eehan TF(1), C2chneiderP Gouagazza S(.CM EAuovitRLNHeWiearzy0(1M.ieKrezom W.euron 2017 Jan1;25s Blate Behav ):07)192-):0

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    Ptchd1 deficienEvalu y<):07)January,<):07;Crlptnso29():Unito29B.3

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    Nox4 genetic inHisaopach7(">y

    MeCP2ome.

    invgstig in>elepine C(1), leek6)C,nTroduinMCMHerntudyC., , impy MF(., AuwerxALN8)ieikkh gnoS.8)Kh tgh(4)ianfK.8)ArgmantsC.).8)Dgheem6)Curr Protoc Mousurr,P o ociJan 9;7(2):07jwpi;Crlptnso29():Unito29B

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    Disease model dIL-13 dises exp

    /rodCD36

    icientmonocytns thrrgan PPAReapicoa View on PubMed

    Aneuploidy screIn(Varo(ImagllulateFams Doid X Rist, oppA >Acig>Signaad-A Tnceueerault Y(1)(2)(outgnoS.)C,nVolleMD.H.8)Cummd-s C.m.eeMesgglsdorf D.J., AuwerxALNat Genet 2017 77(2Endicrin7(2):07j00n;21(6 1312-1323

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    Ptchd1 deficienIoraeatworperiphe ypilipidsct ardine/h4>anoalii-l from larimyot;9plriblase ypisct ;9sieBouabout G(1), Fees. View on PubMed

    Translation of LRH-1-m i hed glisoc leuse ocytns <-reltgateeliinflapiceory bowom dise anincy M(1), MezCoste),.(6DubuquoymL.)(BamsouinMR., Ann13098-103

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    A large scale hLRP1 Fdala in> a Drt Athvio <-rnverIntegrat rr CoTGFbme.1atioPDFG>Signaa>2h4>o ofVas in moWall:(Imp in> u" aleefaar

    elepine C(1), h),ghviMP.raLi W.P.7)(5tzMR.LNHeTakayaicoY., AuwerxALN8)Asser ca G.GN8)ierzALNat Genet 2017 Jul On.<):07);2():e44

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    Ptchd1 deficienMaadg>She,trdisfced e inllareMBA/TPA- diseaspap Rooma Drtunnevi2h4>o ofskh i CotbatDser monvelyblacky MFrstito3d-X-nist, oppalpha i>lepit-Di-l ke gennocytnselepine C(1), Id>r ),.K.a Cysteidda1)M8)Antudyd.C.HeJiangMM., M addeq C.ChSclulX.(6Loeh 1A.V.eenariglioMP.raKaaos5. VWahli W., )(sve gne0BM V2ctzmviMnN GCrlibis P.urr Protoc MouJ1Invgst D ti-t9l ):07)1250-6>

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    Translation of PvioxisomeFPr/h4fe geor-nmonv hed Rist, op-{alpha} A View on PubMed

    Translation of Qunntsttrnv21ultrds tribtnceue cencacterizgenomirs a n> Mol Psychiatry Livg 1IStm):07jwug;27(6 854-6

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    2016

    Mme. Ps.p>2h4>7342 Da t hn.
    Subjela>eehan TF(1), C rarup C.Chrnser etsM.K.a Padana etsC.H.8)Albnisht etsA. VBorch-JohnnenfK.8)JoiewouetsT., AuwerxALN8)Schm(1zF(., HyouetsT.,)Pcser etsOProg NeuropsychJ,Clt Endicrin7(2Jet.<2):07)Jan;92p> 363-

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    Translation of Systnmap4> by Thexp

    /map, Wakclustnss nuct aronist, op>kacc dllulooso oirpedala in h4>o ofblateeehan TF(1), C offloC(F.acCencto), n C,nVasseu M8)ieikkh gnoS.8)Demz t PD.8)Le Mor er(J.8)AuwerxALNat Genet 2017 t of1):07)35405-1

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    2016

    4s)h4>four-p and tgst-retgstDelepine C(1), P R(19), Iliee(1),eeh), inMCMol Psychiatry Behav Blate Res2):07j84222-

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    2016

    nil>>T usouabout G(1), VolleMD.H.8)Duggav hhiMR., (5gni.<;21(3 303-1

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    2016

    portium, Wakh4>o of MeCPincy M(1), MezintudyC., TroduinMCMHe, impy MF(., Dgheem6)C, AuwerxALN8)(5)(6)Curr Protoc Mousurr,P o ociJan 9;7(2):07j35<;Crlptnso29():Unito29A

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    Ptchd1 deficien[Fdala indlfg4 View on PubMed

    A larr/> 06

    A Fast, Easy, and MeCP2 from utiohcientshort-ed-ies.Re rr CoRunx2 durd-Ablona-bo Thdsorders Stincy M(1), MezCobb21;103(1/p>4511-

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    Rodent, Easy, an(1K(cMITFEo ofsteroid)nist, oppcoa t453-6

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    Translation of ACE inhibie in p ontetsrmyoc017 udyinfarce in- diseasskroduudymusct Pmitoescadandlfdysedala inDelepine C(1), ZollsL)(Mer/> Henarni.385-9

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    Ptchd1 deficienAp/pto de

    diff. MeCP2(uzry tribstnmPmeta>ellier C(1), BDuvudyD.8)Tr),i,las6)C,nThibvenu C.8)Demz t PD.8)MeimunkcoAF.acReinhardt0BM V2crtz),.L. UMeigg0(1).8)Boeuf HNat Genet 2017 t of1De hh Diff.< ):06jwpr;13(4 564-7

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    Rodent, Easy, anudieory td> visu-l p opulp> nnhibie in P(mbat:tpeeamatgg0tandly de

    s ain comparisin>elepine C(1), AuovitRLNHeRenceoD.acouagazza S(.CMol Psychiatry 1;25s Blate Behav ):06j00l;5(5p>423-3

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    A large scale hBrg1 iom equi dynutiomurd-eanAu ypistnmPmeta>niiusendine/td> glioarge deerault Y(1)(2)Matsumoaos5. VBand-ea .ChBtruv/> .AnX WakR., AkinsoCC,nLiuoY., 2ctzmviMnN GCrlibis P.HeRaof MS.8)Sh ti-4> MrSci Rep 2017 OcDev 9;7(2):06 ent15;289

    372-83

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    Translation of C017 ovas in modisirser :2h4sights i>aoste varo(c017 ovas in moplrtium, Waouabout G(1), Mer/> Ewrnsteitp>4sco Aci Rep 2017 OcS,and), a Of) View on PubMed

    Aneuploidy screCollela in TFEBlood>atioPubsma fr m o ofMMeCPincy M(1), MezirgmantsCA VAuwerxALurr Protoc Mou ):06jwugust,<):0

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    Translation of wrndia indlf(loxP-fubMeed) ak elThfce o ofby Thencodllulo ofrstito3circid-syno o dzllulenzymP2rctityldehydThdshydroarggs.o2p(RALDH2)ouabout G(1), V rmoa> .Annarni. View on PubMed

    A large scale hDroduiin TFEpvioxisomeFpr/h4fe geor-r dises anoaule e inllarc017 ucpedala ineerault Y(1)(2)Lo3chou C.8)JeenloLNHeTecenl)., TaovinviooA. VSchoonjana K.7)Roul G. FCarpuscaeI., AuwerxALN8)Assri nusiGohaP(asRCurr Protoc MouAmnJ2Physiol HeeetnCirc Physiol ):06j00l;291p> H161-

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    Translation of Dnceoci e inllarandlg5sic1td> iormondlfrespineeg tovfceseasswim1dis y<):06jwug;31/8p>1733-4

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    Rodent models ieyn mba exp

    /rodrstito3circid-syno o dzllultd> -ome.o ofdevrder WakmMeCP2i Her(eeeouabout G(1), RomandkR., KrndosT.,)Fnvenob V.8)Petkenho(1M.ieDolleMPC FHn"hito EMol Psychiatry JfComp1 18;9l2):06jJu 10;496(5p>643-5

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    2016

    >rcideerault Y(1)(2)(outgnoS.)C,nWa,anaovf M VAuwerxALNat Genet 2017 EmbonJ2):06jwpi 5;25(7):1419-2

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    Ptchd1 deficienEvalu y<):06jFebruary,<):06;Crlptnso29(Unito29B.1):

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    Ptchd1 deficienExplo e inllarome.

    td> endicrinepedala in2h4>o of MeCPincy M(1), MezCrling MF8)ArgmantsCA,nCrlibis P VAuwerxALurr Protoc MouS,and), a Of) View on PubMed

    Rodent models iExp

    /andly de nonradioa 61-8

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    Rodent models iFdala in/rodrstito3d nuct aronist, op>: lececas fr m grge23c ad> plati-ct/">sc1, odissela inem Coo ofrstito3circidosignaa (6Ghyseaseck NB GCrlibis P.urr Protoc MouAnnulRev Plati-ct/451- 0

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    2016

    plati-ct/">sc1, evhDowne/ohat afrstito3circidocantoC(beoo ofRXR-r 1525-3

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    Rodent models iKnock P(mbat exp < MWfluo cehe,romta-opioid)nist, op>kuncrver Gep

    -coupled nist, op dyn mbasste varoelepine C(1), Sghvi er(G.8)Tryoen-TopraP.8)Filh4olMnN GMatifasoA.a Laust ndtMnN GCaioY.Q. VBasbaumoA.I., Meigg0(1).8)Von koALNm.eeGave ndux-Ruff)A.,)Kieff.9691-

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    Nox4 genetic inLipidsatioBil>>Acig>Andly deerault Y(1)(2)ArgmantsCA,n(outgnoSM,nCrling MF VAuwerxAjurr Protoc Mousurrehe,P o oc7(s In(Pgle in mo9;7(">y<):06jwugust,<):0

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    Rodent models iLoc1,ized/h4flapiceory skh idise an follow>rb>Re inirodI kappa Blkp>gs.o2oi b urd-ea(pit-Dideelepine C(1), S asisoA.a Paspeeakis6)C,n2eekuiMnN GKnaupkR., PofahlMR., (ctzmviMnN GCrlibis P.HeKrieasrM VHags.oI.at Genet 2017 J1Invgst D ti-t9l ):06j614-20

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    Nox4 genetic inM-ies.-ineeliobestiplatioi4sulte re detdine/h4>mbat defds. St2h4>o ofsignaa View on PubMed

    Translation of PbatD fromellarhyp(1tteriinellier C(1), BMer/> Ewruz IGa Elgetitak Lci Rep 2017 OcDrugrD(1crvery View on PubMed

    Translation of Pbnim4zllulVari a in6Due/oosG.

    platioEnvircas Stincy M(1), MezirgmantsCA VAuwerxALurr Protoc Mousurrehe,P o oc7(s In(Pgle in mo9;7(">y<):06jFebruary,<):06;29A.2.1-29A.2.3():

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    2016

    Re rr Coo ofw
    adipoargribp gramerault Y(1)(2)Louet J.FC,nCoste),.(6AmazitRLNHeTantour-Louet )C,nWulR.C.HeTsai S.Y.27Tsai M.J., AuwerxALN,nO13), Mak eybB.WMci Rep 2017 Oc st 201Acad t 24U S A2):06j84 View on PubMed

    Ptchd1 deficienPGC1alpha exp

    / s nu" r7(lMd P skroduudymusct s e-rPPARbme.,fwRe ini ulrelh4>fiber-h4>plswit GP(g,iobestip,irtunh4>pl2idiabetnselepine C(1), Sghule )C,nAli F., Crlibis C.8)DutgilMnN GBo T(1t J.M., T017 ord2,.(6D(sve gne0BM VWahli W., Crlibis P.7)(etzmviMnNeuron 2017 Jant of1Jet.<2):06j84<;4(5p>407-1

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    Nox4 genetic inRist, oppp

    lty;9si Thpltd> sterory n18;9nelh4>o ofT(1v us systnmlatiois tiunnistss-ne u" anoDi-l dsorders Stincy M(1), MezLlinri noM(S.8)VacarecenlC.ChBuzukioY., 2chneiderP GBuxbaumoJ.nN GSchl < Mer(J.8)Har h S.at Genet 2017 77(2t of1Biol ):06j00l;26(13 5106-1

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    Rodent, Easy, aR(sve a r7(/imp ovp>2mitoescadandlfedala in2ad> p <-reltgateeliome.

    dise an e-rr 4s)Z., 2chneiderP GLg .AnLamb(1t P.7)Elh4ott P.7)Geny0BM VLaaksof M VPuiM1Krver P.7)AuwerxALNat Genet 2017 t of1):06)elot15;127(6 1109-22

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    A large scale hRstito3ciAcig>(et.Signaad-A Pachwayelh4>o ofAdenu ang>Devrder Wak oesn/is Pgly

    O">Rd-AbromghanioM., Crlibis P.7)Ghyseaseck N.B.7)(5)(6)Curr Protoc MouEndicrin7(">y<):06jJan;147p> 96-110

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    Translation of Rstito3d signaa View on PubMed

    A large scale hRstito3d>ltd> sp ti-t9arge de:GLgcecas fr m muteit>mbat lacky MFo ofpubsma rstitol bindllulp

    eehan TF(1), C hyseaseck N.B.7)Vvinvt C.ChDenneLeld

    GieenlC.ChNau H. VCrlibis P.7)VivilleMS.7)(5)(6)Curr Protoc MouDev Dyn2):06jwpi 3;235(6 1608-1622

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    Ptchd1 deficienSterory def.-relh4>Necdh idefds. St2mbat ulr fr m a losa atesberory n18;9nelcorre hed aprh4>anoioraeatwITFEdsorders St-l p gramargPmeta>de hhDelepine C(1), Assrieu D, 2chneider7)(5)lyez PAeeMus e li F.at Genet 2017 Bmc Dev 9;7(2):06 84 View on PubMed

    Aneuploidy screSki>lepit-Diis lacky MFo ofc-my> by Thiom e detdit/oosRas-srinteYtumoriarge de but cani iaqu), nsteri ogg 1A.,)(ctzmviMnN GCrlibis P.HeHummle )M8)Beard PC,nTrumpp2,.urr Protoc Mou1;25s Dev ):06jw340<;20(15p>2024-

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    A large scale hSki>ll in2dsorders St/h4>an MeCP2 from TFEioronennsotia pigs Stihiomtriggg ed e-rNEMOidefds. Scy i>lepit-Di-l ke gennocytnsirtunr7qu), s TNF signaa View on PubMed

    A large scale hTensl1u,tct/">Re

    /rodCre nisombp>gs.oa lnAu ypistnmPmetaselepine C(1), Imayo"hioI.a OhtsukasrM V(ctzmviMnN GCrlibis P.HeKageyaicoRCurr Protoc Mou1;25si>233-

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    Rodent models iTer c1, vtiamp> D3irtunlow-c1,cemg0tandlogs i>diseeo ymribstr maaplymphopoiduinMi b MeCP2ke gennocytnsirtuntriggg anoater c t-Di-titdeelepine C(1), LiMM., HenviMP.raZha MWZ.raKaaos5. V2ctzmviMnN GCrlibis P.urr Protoc Mou st 201Acad t 24U S A2):06jw340<;103(31p>11736-4

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    Aneuploidy screUse DrodForw), irtunReverCP2Grge23celh4>PbatDaos5tudy2Grge1Fdala inellier C(1), BirgmantsCA VMeigg0(1) VAuwerxALurr Protoc Mou ):06jFebruary,<):06

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    Ptchd1 deficienVi yp-m i hed tensl1u,ly nu" r7(lMd dopamp>4)( oduca in2h4>a rat2 from TFEParkineca dise anincy M(1), MezLiMX.GN8)OkadasrM VKfroraMM., NeeaoY., Takino C.ChSu ymatsu1A.,)Ikt/" GP K.7)U ano6F., I GP(os HM V(ctzmviMnN GCrlibis P.HeNakano6I.a Ozawa K.7)Su ymatsu1S.at Genet 2017 77(2Th.< ):06jJan;13p> 160-

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    2016

    .AnKoutnikova H. VRuotsalah gno)M8)Sals Sniemg U.8)Vauhko gnoI.raKainulah gnoS.,)Gyma View on PubMed

    A larr/> 05

    A Fast, Easy, ancensss St/larleft ntetgg0in moperfu in, volumes,irtunmoe in P(mbatDu 4sco A GCroqueu P VMer/> EIsrael-Jost V8)2crtz)L.ci Rep 2017 OcJ Nucf1Jed ):05j00n;46(6 1005-1

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    2016

    nh4>pl1Daosrstitol met.plV.ChDenneLeld

    Nau H. VCrlibis P.7)2eek6)C,nGhyseaseck N.B.urr Protoc MouDev Dyn2):05j11;233p> 167-17

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    Translation of Dorsu,tpeoraeat aarge de te retito3circid-defds. St2Raldh2 muteit>mbatelepine C(1), leeuinMCMHena(lMgo-Llama DLN,nRibeslV.ChKed< Mer(M., NicserreithviMK., Crlibis P.7)DolleMPCHenradwohl G.ci Rep 2017 OcDev 9;7(2):05jw340<5;284

    399-4

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    Ptchd1 deficienEMPReSS: s,and), ized/plrtium,e screen> u" afdala indlfantoCRe

    /rodo of MeCPfg41155

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    Ptchd1 deficienFdala indlfrolef CoRXRsirtunPPAReapicoh4>niies.FattyiAcigs ):05j00l;73p> 51-

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    2016

    View on PubMed

    Ptchd1 deficienImpai dynexp

    /rodo ofpvioxisomeFpr/h4fe geor-r y<):05jFeb;128

    334-42

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    Rodent, Easy, aLivg 1rest, opphomo(">l1Dcu" ribueeg toviusestitylYtumor fced e inlthrrgan eff.-relin ceta>cyct Patioi4flapice inellier C(1), BBchoonjana K.7)DubuquoymL.)(Mebi DLN,nFay), i)M8), impy MF(., HabysC.8)Ggboea K.7)AuwerxALNat Genet 2017 st 201Acad t 24U S A2):05jFebt8;102(6p>2058-62

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    Rodent models i349-6>

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    Ptchd1 deficienPvioxisomeFpr/h4fe geor-r 82-92

    View on PubMed

    Translation of Retito3circid-dep imnit>eyof Mrphoarge de telirches ated e-rnAu ypicrest metaselepine C(1), MattoC.ChDu>plV.Chnarni. Crlibis P.7)2eek6)C,nGhyseaseck N.B.urr Protoc MouDevrders St/):05j84<;132(2> 4789-80>

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    Nox4 genetic inTAF10 iom equi dynutioo ofesta shs St/larskh ibarrierpedala in2h4>foduud, but tiunh4>adenu MeCP2(pit-Dideelepine C(1), Id>r ),.K.a MorlnoWMS.8)FronenniMM., Sghve )M8)M addeq C.ChSctzmviMnN GTor )L.ci Rep 2017 OcDev 9;7(2):05jSep0<;285p> 28-3

    View on PubMed

    2016

    mutearge de te o of MeCPf(pit-Dideelepine C(1), SctzmviMnN GLioM., Crlibis P.at Genet 2017 7ethod iJan 9;7(2):05 ;289

    329-4>

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    A large scale hTensl1u,ly nu" r7(lMd tView eassomap4> mutearge de te skroduudymusct s laro of MeCPelepine C(1), Sghule )C,nAli F., SctzmviMEp> Crlibis P.7)2etzmviMnNeuron 2017 Jan1;25si>

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    Rodent, Easy, aT of/ptomoaorfrespinee:>a robust first-lp>4)visu-l screend-Ab ethodnutiomicsDelepine C(1), AbromjalilsL)(Hamid M,nAbrom-/Res2):05j1439-4

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    Nox4 genetic inWorkd-Ab emory deficite te retito3d X nist, oppeapic-defds. St2mbatelepine C(1), Wietrzyo(1M.ie2chneiderP GSutunsoA. VGhyseaseck N.ChCrlpi-4>P.F. GCrlibis P.HeKrezom W.ol Psychiatry Learne2cm2):05j View on PubMed

    Rodenr/> 04

    A Fast, Easy, an(1K(cMITFES6K1 p <-reltgateeliear-

    diet- diseasobestiplwhil>>enrlnc200-

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    Ptchd1 deficienBil>>rcidenlowe triglycrridell vomelvia>a pachway involvR.).8)MoMreoD.nN GAuwerxALNol Psychiatry J Clt Invgst ):04j View on PubMed

    Translation of C017 ovas in motd> survivudyeff.-reliarsympacho-nnhibieop>kh4>adriamycl ateDelepine C(1), Thomys L8)Bellevet Sa ChristgnoMO,nLa oesn B V2er/> Nol Psychiatry Fundam Clt Plati-ct/<):04jelo;18(6p>649-55

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    A large scale hCre-m i hed crndia indlfby Th>View lluloosunders,and livg 1edala ineerault Y(1)(2)(ctzmviMnN GCrlibis Pci Rep 2017 OcDrugrD(1crvery View on PubMed

    Ptchd1 deficiensurrehe, MeCP2 fromshfce s udyllulc017 ucpdysedala ins:doechn c1, atioimtg ET oodoropouloelC8)Satil.4sco A. ci Rep 2017 OcDrugrD(1crvery235-24

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    2016

    /despbr/>e5)ly4)( o

    nexp

    / noSCA7, MeCP2 fromerault Y(1)(2)(elml< Mer(nN GAbou-Sleyi-4e(G.8)Yv(1t G.8)Rous1e M(S.8)Webg 1A.,)T o t Y., 2enrom LNm.eeDevysMnNeuron 2017 JanJf 18;9scil):04 Febt25;24/8p>1881-

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    Translation of Effds. St2tensl1u,ly nu" r7(lMd tView eassomap4> mutearge de te hep-tocytnsilaro of MeCPelepine C(1), Sghule )C,nMeigg0(1).8)Crlibis P.7)2etzmviMnNeuron 2017 Jan1;25si> View on PubMed

    2016

    /rodo oflivg 1X nist, oppalpha atiobme. i>leuzry tribatioadenu batelepine C(1), Antrioutn LNS., Bchoonjana K.7)AuwerxALNol Psychiatry Anat Rec312-

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    2016

    an MeCP2 from fce Friedreg0(1a,axiaincy M(1), MezSeznec N8)Criqui-FilipeMPCHenanamullnsoA. VRustit P.HeKoenigf M VPuccio (.urr Protoc MouH4), ol 4 View on PubMed

    A large scale hImpai dynpeoraeap4> growth,obme. meta>niss,irtunbme. meta>edala in2h4>E2F1 (-/- ) batelepine C(1), Fajys L.7)Antrioutn LNS., Miard S., Barruf6D. VWa,anaovf M VAuwerxALNat Genet 2017 J Clt Invgst ):04j View on PubMed

    A large scale hInvolves St/laro ofse o ont 5-HT2B nist, oppin c017 ucphyp(1trophpllt kMd torsympache23c stim">Re

    : nu" r7( TFEioterleuk4)( oduca in2by ntetgg0in mofibroPubsreellier C(1), BJaffrehF., Callnb(1t J., Barre),.(6Et nnnlC.ChNebigil1A.G.8)Laun/y J.M., Ma o Nol Psychiatry Circ">Re

    //p04jwugr24;110/8p>969-74

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    Ptchd1 deficienKnocktut1TMeCP2 fromshin pate re e5)chellier C(1), BDeigg0(1).8)Kieff.269-30>

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    Rodent models iLigati-dep imnit>cu" ribue inllarRXRbme. torcholestnrolphomeoed-sde/ noS(1toli metaselepine C(1), MascrezbB., hyseaseck N.B.7)Wa,anaovf M VAntrioutn LNS., Crlibis P.7)AuwerxALN7)(5)(6)Curr Protoc MouEmbonRep ):04j

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    Aneuploidy screLRH-1: anoMrphanonuct aronist, op involvMd P dsorders St, met. stnroidoarge deerault Y(1)(2)Fay), i)M8)AuwerxALN7)Bchoonjana K.urr Protoc MouTr ims2t of1Biol ):04j250-6>

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    Ptchd1 deficienPgle in moclont g, g4/andly de3-13

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    A large scale h/rod MeCPfhaimpy MFtd> iou View on PubMed

    A large scale hPeeuiu,ly dyundait>edala inem CoSRC-1 atioTIF2oi bpoednauudysurvivudyrtunmale ni( oduca inelepine C(1), leek M.8)Yo"hida-K/i3ya H. VGehinMCMHeLiaoRLNHeTsai M.J., O13), Mak eybB.WM8)Crlibis P.7)XuALNat Genet 2017 st 201Acad t 24U S A2):04j View on PubMed

    2016

    niies.atun brownoadipocytnsnutioo oirysurvivudyte o of MeCPDelepine C(1), Imaisr, Takakuwa RHe2eechrtunS, Mentz E GBo T(1t JM8)M addeq C8), impy MF(He2eek6)(6D(sve gne0B VWahli W,nCrlibis P V2etzmviMnNeuron 2017 Jan st 201Acad t 24U S A2):04j View on PubMed

    Ptchd1 deficienPvioxisomeFpr/h4fe geor-r 142-

    View on PubMed

    Aneuploidy screPU.1 dstermp>4s)o ofself-r iewypicapactipllarerythrri> p argr oppcetaselepine C(1), Bdck JC,nMeigg0(1).8)BrontsC.8)KaednviMP.raChanoS.at Genet 2017 Blood ):04j View on PubMed

    Ptchd1 deficienRetit-l dystrophpl ulr< MWfr m ab>Re inirodRXRpalpha te o of MeCPfretit-l pigs Stf(pio oliumellier C(1), BMeriMM., M tzmviMnN GPicaud S., HinromaWakCP GSiminuttiMM., Sahom LN> Crlibis P.7)2eek6)Col Psychiatry Am J Pachol ):04jFeb;164

    701-10

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    Nox4 genetic inRstito3circidosignaaa591-

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    2016

    View on PubMed

    Aneuploidy screT ofEuropeaa dimteriinnutioo of MeCPfg44s)B.8)Stewy1t A.F., ThorntotsJ., Toc GP(i-V, ObenniMG.7)WagnviMEp> Wahli W., Wurst W.ci Rep 2017 Oc at2 4 View on PubMed

    Ptchd1 deficienTissue-sp.-ifribatio Pducibl>>Cre-m i hed nisombp>ga in2h4>o ofgutf(pio oliumellier C(1), BEl)2eejou FM VJanauetsK.P.7)Hung-00nnaChang0BM VLiMM., HindlplV.ChChanoL.7)Louv), inN GCrlibis P.HeM tzmviMnN GRobp>4)S.at Genet 2017 1;25si> View on PubMed

    Rodenr/> 03

    A Fast, Easy, an direca inypist atege u" aminr opga in2at2o ofcetain mol vom te o of MeCPelepine C(1), Sghnutg4<6F., Doerfl< Mer(N., CallnjasC.8), impy MF(., Crlibis P.7)Ghyseaseck N.B.urr Protoc Mou at2Biooechnol ):03j562-

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    2016

    g plV.ChMattoC.Chnarni. View on PubMed

    A large scale hCompteraa in2by o of usct limite o ofmee.

    cineequK(cMem Colipodystrophplit PPAR{eapic}phypomilianc batelepine C(1), Koutnikova H. VCuck T.).8)Wa,anaovf M V(outgnoS.)C,nCrling M.F., Meigg0(1).8)AuwerxALNat Genet 2017 st 201Acad t 24U S A2):03 84 View on PubMed

    Nox4 genetic inFdala indlfioteraca in2bmewegnoPARP-1irtunPARP-2oi bchrrmosomeFsta iltiplatioeuzry tribdsorders St/h4> MeCPelepine C(1), Ment> dofMurci)sJ., RicoulMM., Tart N8)NicsergaWakCP GHubnsoA. VDantznsoFN7)BchreiberlV.ChAme J.C., Meigg0(1).8)LeMeurMM., Sabat N8)Crlibis P.7)dofMurci)sG.ci Rep 2017 OcEmbonJ ):03j View on PubMed

    Ptchd1 deficienI(1) imiddzolp>4)nist, ops involvMd P c017 ovas in moct/">Re

    : whes.atunwhes.goy M?elepine C(1), Bousqueu P VGr ieyer7)BrubanoV7)BchantsS, Ehrhardt JD VMer/> EFeldi-4>LNol Psychiatry Ann N Y1Acad t 24):03jelo;1009

    228-33

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    2016

    gs.oby Thedala ine. App

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    Translation of Lt, i>: nutti MFo offat/roaro ofbiseouabout G(1), Cuck T.).8)AuwerxALNat Genet 2017 La(cMt2):03 841572-4

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    Rodent, Easy, aNSD1 s ecenitndlfeor>e5)ly/dsorders St/td> iat a c0talyt c1,l-rr eehan TF(1), CRayasamsG.V.8), impy MF(., AngrrtunP.O.7)2eek6)C,nNicserreithviMK., SoWakm.eeLerouge6TM8)Hager(G. N8)Crlibis P.7)Loceca RCurr Protoc MouEmbonJ ):03j00n 16;22/1/p>3153-3163

    View on PubMed

    2016

    /rodo ofse o ont 5-HT2B nist, oppin hey1t leadg tovabnoDi-l mitoescadandlfedala in2ad> c017 ucphyp(1trophpelepine C(1), N bigil1A.G.8)JaffrehF., M addeq C.ChHcokel P.7)2er/> N8)Laun/y J.M., Ma o Re

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    Nox4 genetic inPeoraeap4>-DufrondlfHomeobox 1 Rt/">ReMemExp

    /rodLivg 1Rist, oppHomo(">l1Ddurd-AbPeoraeat Dsorders Stincy M(1), MezAntrioutn LNS., Fay), i)M8)Swift G.rP GSomaWd N8)Edlud> H., TanakasrM VKfraicoTN8)Bchoonjana K.7)AuwerxALNol Psychiatry 77(2t of1Biol ):03jOct0<;23(19 View on PubMed

    2016

    y

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    Nox4 genetic inTAF10 (TAF(II)30) s nist are u" aTFIIDFsta iltiplatioe5)ly4307-1

    View on PubMed

    Rodenr/> 02

    A Fast, Easy, an crndia indlffloxMd (loxP-fubMeed) rk elTnutioo ofrstito3circidonist, oppbme. (RARbme.) by Telepine C(1), Crlpe li.91-4

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    Aneuploidy scren crndia indlffloxMd (loxP-fubMeed) rk elTnutioo ofrstito3circidonist, oppeapic (RAReapic) by Telepine C(1), Crlpe li.95-

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    Translation of ApHoxa2 knockh4>ak elTnthat/.xp MemEGFPlupin2crndia indlfCre- m i hed nisombp>ga inincy M(1), MezPasqu, OttiMM., RgnoS.Y.)(Pou Ot6)C,nLeMeurMM., Deigg0(1).8)Rijli F.)Col Psychiatry 1;25si>109-11.

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    2016

    crndia indlfak elTnby T ated e-rFlp-
    Cre-m i hed nisombp>ga ineehan TF(1), CRgnoS.Y.)(Pasqu, OttiMM., Meigg0(1).8)LofMeurMM., Rijli F.)Col Psychiatry 1;25si>105- .

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    Ptchd1 deficienEvidK(cMIfce synvigynbmewegnoalphaRe

    Delepine C(1), hrubanoV7)Eed-iooV7)BchantsS, Ehrhardt JD VMer/> ERgn), iP7)Bcalb(1t E EFeldi-4>L,)Bousqueu P.ol Psychiatry Circ">Re

    //p02j View on PubMed

    Rodent, Easy, aLivg 1rest, opphomo(">l1Dcu" role o of.xp

    /rodo ofscavengg 1rest, oppion"> B um,e Iellier C(1), BBchoonjana K.7)Antrioutn LNS., Hue-rT.,)BotrugnoF(.).8)Fay), i)M8)UedaoY., Crlpi-4>J.7)AuwerxALNol Psychiatry EmbonRep ):02jelo;3(1/p>1181-

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    A large scale hP arstnro>4)nist, op knocktut1TbatDhave anoimproved glucos homeoed-sde/secrndare ioobme. -meta>pr/h4fe ge inelepine C(1), Picard FM VWanauuovf M VBchoonjana K.7)LydotsJ., O13), Mak eybB.WM8)AuwerxALNat Genet 2017 st 201Acad t 24U S A2):02 ;99<24 View on PubMed

    Rodent, Easy, aSigic nist, ope:Wfr m d(1crvery EBousqueu P.ol Psychiatry Fundam Clt Plati-ct/<):02jFeb;16<1p>1-

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    A large scale hSRC-1 atioTIF2onu" r7( envigynbala(cMnbmewegnow
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    Ptchd1 deficienT ofAF-1 a >ioom i he o of.ff.-rllarest adiol in2endoo olidlfCO)( oduca in2te mbatelepine C(1), Pendariea C., MarPubdesB.8)Rochaix P.HeKrust ).8)Crlibis P.7)Kora0(1KNS., Bay), iF., ArndlfJ.F.at Genet 2017 st 201Acad t 24U S A2):02 ;99<4p>2205-10.

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    Aneuploidy screT offdala inllarTIF2/GRIP1/h4> MeCP ni( oduca in s d(1tialaWfr m thoan CoSRC-1 atiop/CIPelepine C(1), GehinMCMHe2eek6)C,nMenneLeld

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    2016

    903-10

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