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Please mind that the following list is still in progress and non-exhaustive, and that most of our USERS publications are rather classified as ICS publications since some of ICS staff are coauthors.

2017


A molecular mechanism for the topographic alignment of convergent neural maps.

Savier E1, Eglen SJ2,3, Bathélémy A1, Perraut M1, Pfrieger FW1, Lemke G4, Reber M1,3.
Elife 2017;Mar 14;6. pii: e20470

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2016


The DNA methyltransferase DNMT3C protects male germ cells from transposon activity.

Barau J, Teissandier A, Zamudio N, Roy S, Nalesso V, Hérault Y, Guillou F, Bourc'his D.
Science 2016;Nov 18;354(6314):909-912.

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DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for DrugDevelopment in Down Syndrome.

Duchon A, Herault Y.
Front Behav Neurosci. 2016;3;10:104.

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Mu Opioid Receptors in Gamma-Aminobutyric Acidergic Forebrain Neurons Moderate Motivation for Heroin and Palatable Food

Pauline Charbogne, Olivier Gardon, Elena Martín-García, Helen L. Keyworth, Aya Matsui, Anna E. Mechling, Thomas Bienert, Taufiq Nasseef, Anne Robé, Luc Moquin, Emmanuel Darcq, Sami Ben Hamida, Patricia Robledo, Audrey Matifas, Katia Befort, Claire Gavériaux-Ruff, Laura-Adela Harsan, Dominik von Elverfeldt, Jurgen Hennig, Alain Gratton, Ian Kitchen, Alexis Bailey, Veronica A. Alvarez, Rafael Maldonado, and Brigitte L. Kieffer
Biological Psychiatry 2016;Dec 26. pii: S0006-3223(16)33156-0

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Insulin receptor isoform A ameliorates long-term glucose intolerance in diabetic mice.

Diaz-Castroverde S, Gómez-Hernández A, Fernández S, García-Gómez G, Di Scala M, González-Aseguinolaza G, Fernández-Millán E, González-Rodríguez Á, García-Bravo M, Chambon P, Álvarez C, Perdomo L, Beneit N, Escribano O, Benito M.
Dis Model Mech. 2016; Nov 1;9(11):1271-1281.

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A suppressor locus for MODY3-diabetes.

Garcia-Gonzalez MA, Carette C, Bagattin A, Chiral M, Makinistoglu MP, Garbay S, Prévost G, Madaras C, Hérault Y, Leibovici M, Pontoglio M.
Sci Rep. 2016;Sep 26;6:33087. doi: 10.1038/srep33087.

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Pharmacological evaluation of orexin receptor antagonists in preclinical animal models of pain.

McDonald T, Liang HA, Sanoja R, Gotter AL, Kuduk SD, Coleman PJ, Smith KM, Winrow CJ, Renger JJ.
J Neurogenet. 2016;Mar;30(1):32-41.

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Rev-erbα in the brain is essential for circadian food entrainment.

Delezie J, Dumont S, Sandu C, Reibel S, Pevet P, Challet E.
Sci Rep. 2016;Jul 6;6:29386.

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2015


A vitamin D receptor selectively activated by gemini analogs reveals ligand dependent and independent effects.

Huet T, Laverny G, Ciesielski F, Molnár F, Ramamoorthy TG, Belorusova AY, Antony P, Potier N, Metzger D, Moras D, Rochel N.
Cell Rep. 2015;Feb 3;10(4):516-26.

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Early embryonic-like cells are induced by downregulating replication-dependent chromatin assembly

Takashi Ishiuchi, Rocio Enriquez-Gasca, Eiji Mizutani, Ana Bošković, Celine Ziegler-Birling, Diego Rodriguez-Terrones, Teruhiko Wakayama, Juan M Vaquerizas & Maria-Elena Torres-Padilla
Nat Struct Mol Biol. 2015; Aug 3. doi: 10.1038/nsmb.3066. [Epub ahead of print]

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Nociceptin/Orphanin-FQ Modulation of Learning and Memory.

Abdel-Mouttalib O.
Vitam Horm. 2015;97:323-45

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2014


Proteomic survey reveals altered energetic patterns and metabolic failure prior to retinal degeneration.

Griciuc A, Roux MJ, Merl J, Giangrande A, Hauck SM, Aron L, Ueffing M.
J Neurosci 2014;Feb 19;34(8):2797-812.

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Heterozygous deletion of the Williams-Beuren syndrome critical interval in mice recapitulates most features of the human disorder.

Segura-Puimedon M, Sahún I, Velot E, Dubus P, Borralleras C, Rodrigues AJ, Valero MC, Valverde O, Sousa N, Herault Y, Dierssen M, Pérez-Jurado LA, Campuzano V.
Hum Mol Genet. 2014;Dec 15;23(24):6481-94

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Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans

De la Torre R, De Sola S, Pons M, Duchon A, de Lagran MM, Farré M, Fitó M, Benejam B, Langohr K, Rodriguez J, Pujadas M, Bizot JC, Cuenca A, Janel N, Catuara S, Covas MI, Blehaut H, Herault Y, Delabar JM, Dierssen M.
Mol Nutr Food Res. 2014;Feb;58(2):278-88

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The cytosolic carboxypeptidases CCP2 and CCP3 catalyze posttranslational removal of acidic amino acids

Olivia Tort, Sebastián Tanco, Cecilia Rocha, Ivan Bièche, Cecilia Seixas, Christophe Bosc, Annie Andrieux, Marie-Jo Moutin, Francesc Xavier Avilés, Julia Lorenzo and Carsten Janke
Mol Biol Cell. 2014;Oct 1; 25(19): 3017–3027

LEOPARD syndrome-associated SHP2 mutation confers leanness and protection from diet-induced obesity.

Tajan M, Batut A, Cadoudal T, Deleruyelle S, Le Gonidec S, Saint Laurent C, Vomscheid M, Wanecq E, Tréguer K, De Rocca Serra-Nédélec A, Vinel C, Marques MA, Pozzo J, Kunduzova O, Salles JP, Tauber M, Raynal P, Cavé H, Edouard T, Valet P, Yart A.
Pnas 2014;Oct 21;111(42):E4494-503.

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The Gdap1 knockout mouse mechanistically links redox control to Charcot-Marie-Tooth disease.

Niemann A, Huber N, Wagner KM, Somandin C, Horn M, Lebrun-Julien F, Angst B, Pereira JA, Halfter H, Welzl H, Feltri ML, Wrabetz L, Young P, Wessig C, Toyka KV, Suter U.
Brain 2014;Mar;137(Pt 3):668-82

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Microbiota-generated metabolites promote metabolic benefits via gut-brain neural circuits.

De Vadder F, Kovatcheva-Datchary P, Goncalves D, Vinera J, Zitoun C, Duchampt A, Bäckhed F, Mithieux G.
Cell 2014;Jan 16;156(1-2):84-96.

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Intestinal gluconeogenesis is crucial to maintain a physiological fasting glycemia in the absence of hepatic glucose production in mice.

Penhoat A, Fayard L, Stefanutti A, Mithieux G, Rajas F
Metabolism 2014;Jan;63(1):104-11

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Mutation of the palmitoylation site of estrogen receptor α in vivo reveals tissue-specific roles for membrane versus nuclear actions

Adlanmerini M, Solinhac R, Abot A, Fabre A, Raymond-Letron I, Guihot AL, Boudou F, Sautier L, Vessières E, Kim SH, Lière P, Fontaine C, Krust A, Chambon P, Katzenellenbogen JA, Gourdy P, Shaul PW, Henrion D, Arnal JF, Lenfant F.
Proc Natl Acad Sci U S A. 2014;Jan 14;111(2):E283-90

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NOS2 expression is restricted to neurons in the healthy brain but is triggered in microglia upon inflammation.

Béchade C, Colasse S, Diana MA, Rouault M, Bessis A.
Glia 2014;62(6):956-63

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The miR-379/miR-410 cluster at the imprinted Dlk1-Dio3 domain controls neonatal metabolic adaptation.

Labialle S1, Marty V1, Bortolin-Cavaillé ML1, Hoareau-Osman M1, Pradère JP2, Valet P2, Martin PG3, Cavaillé J4.
Embo J. 2014;Oct 1;33(19):2216-30.

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Dyrk1A induces pancreatic β cell mass expansion and improves glucose tolerance.

Rachdi L, Kariyawasam D, Aïello V, Herault Y, Janel N, Delabar JM, Polak M, Scharfmann R.
Cell Cycle 2014;Jul 15;13(14):2221-9

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Cognition and hippocampal plasticity in the mouse is altered by monosomy of a genomic region implicated in Down syndrome

Sahún I, Marechal D, Pereira PL, Nalesso V, Gruart A, Garcia JM, Antonarakis SE, Dierssen M, Herault Y
Genetics 2014; Jul;197(3):899-912.

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Elk3 deficiency causes transient impairment in post-natal retinal vascular development and formation of tortuous arteries in adult murine retinae.

Weinl C, Wasylyk C, Garcia Garrido M, Sothilingam V, Beck SC, Riehle H, Stritt C, Roux MJ, Seeliger MW, Wasylyk B, Nordheim A
Plos One 2014;Sep 9;9(9):e107048

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Domains of genome-wide gene expression dysregulation in Down's syndrome.

Letourneau A, Santoni FA, Bonilla X, Sailani MR, Gonzalez D, Kind J, Chevalier C, Thurman R, Sandstrom RS, Hibaoui Y, Garieri M, Popadin K, Falconnet E, Gagnebin M, Gehrig C, Vannier A, Guipponi M, Farinelli L, Robyr D, Migliavacca E, Borel C, Deutsch S, Feki A, Stamatoyannopoulos JA, Herault Y, van Steensel B, Guigo R, Antonarakis SE
Nature 2014;Apr 17;508(7496):345-50

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2013


Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening

David Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant,Tom Weaver, and David West.
Dis Model Mech. 2013;May-Jun;6(3):571-9

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Robo3-driven axon midline crossing conditions functional maturation of a large commissural synapse.

Michalski N, Babai N, Renier N, Perkel DJ, Chédotal A, Schneggenburger R.
Neuron. 2013;Jun 5;78(5):855-68

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Climbing fiber input shapes reciprocity of purkinje cell firing.

Badura A, Schonewille M, Voges K, Galliano E, Renier N, Gao Z, Witter L, Hoebeek FE, Chédotal A, De Zeeuw CI.
Neuron. 2013;May 22;78(4):700-13

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p53-PGC-1a Pathway Mediates Oxidative Mitochondrial Damage and Cardiomyocyte Necrosis Induced by Monoamine Oxidase-A Upregulation: Role in Chronic Left Ventricular Dysfunction in Mice

Christelle Villeneuve,1,2,* Ce´ line Guilbeau-Frugier,1,2,* Pierre Sicard,1,2 Olivier Lairez,1,2 Catherine Ordener,1,2 Thibaut Duparc,1,2 Damien De Paulis,3,4 Bettina Couderc,2 Odile Spreux-Varoquaux,5 Florence Tortosa,1,2 Anne Garnier,6 Claude Knauf,1,2 Philippe Valet,1,2 Elisabetta Borchi,7 Chiara Nediani,7 Abdallah Gharib,3,4 Michel Ovize,3,4 Marie-Bernadette Delisle,1,2 Angelo Parini,1,2 and Jeanne Mialet-Perez1,2
Antioxidants & Redox Signaling 2013; Volume 18, Number 1

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Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease.

Nemazanyy I, Blaauw B, Paolini C, Caillaud C, Protasi F, Mueller A, Proikas-Cezanne T, Russell RC, Guan KL, Nishino I, Sandri M, Pende M, Panasyuk G.
Embo Mol Med. 2013;2013 Jun;5(6):870-90.

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Huntingtin mediates anxiety/depression-related behaviors and hippocampal neurogenesis.

Ben M'Barek K1, Pla P, Orvoen S, Benstaali C, Godin JD, Gardier AM, Saudou F, David DJ, Humbert S.
J Neurosci. 2013;May 15;33(20):8608-20

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Homeostasis in Intestinal Epithelium Is Orchestrated by the Circadian Clock and Microbiota Cues Transduced by TLRs

Mukherji A, Kobiita A, Ye T, Chambon P
Cell 2013;May 9;153(4):812-27

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Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription.

Lam MT, Cho H, Lesch HP, Gosselin D, Heinz S, Tanaka-Oishi Y, Benner C, Kaikkonen MU, Kim AS, Kosaka M, Lee CY, Watt A, Grossman TR, Rosenfeld MG, Evans RM, Glass CK.
Nature 2013; Jun 27;498(7455):511-5.

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Hepatic glucose sensing is required to preserve β cell glucose competence.

Seyer P, Vallois D, Poitry-Yamate C, Schütz F, Metref S, Tarussio D, Maechler P, Staels B, Lanz B, Grueter R, Decaris J, Turner S, da Costa A, Preitner F, Minehira K, Foretz M, Thorens B.
J Clin Invest. 2013;Apr;123(4):1662-76.

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The STRA6 receptor is essential for retinol-binding protein-induced insulin resistance but not for maintaining vitamin A homeostasis in tissues other than the eye.

Berry DC, Jacobs H, Marwarha G, Gely-Pernot A, O'Byrne SM, DeSantis D, Klopfenstein M, Feret B, Dennefeld C, Blaner WS, Croniger CM, Mark M, Noy N, Ghyselinck NB.
J Biol Chem. 2013;Aug 23;288(34):24528-39.

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Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor.

Sun Z1, Feng D1, Fang B1, Mullican SE1, You SH1, Lim HW1, Everett LJ1, Nabel CS1, Li Y1, Selvakumaran V1, Won KJ1, Lazar MA2.
Mol Cell. 2013;26;52(6):769-82

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Investigating the contribution of VAPB/ALS8 loss of function in amyotrophic lateral sclerosis.

Kabashi E, El Oussini H, Bercier V, Gros-Louis F, Valdmanis PN, McDearmid J, Mejier IA, Dion PA, Dupre N, Hollinger D, Sinniger J, Dirrig-Grosch S, Camu W, Meininger V, Loeffler JP, René F, Drapeau P, Rouleau GA, Dupuis L.
Hum Mol Genet. 2013;Jun 15;22(12):2350-60.

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JAK2V617F expression in mice amplifies early hematopoietic cells and gives them a competitive advantage that is hampered by IFNα.

Hasan S, Lacout C, Marty C, Cuingnet M, Solary E, Vainchenker W, Villeval JL.
Blood 2013;Aug 22 ;122(8):1464-77

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Dynamin 2 homozygous mutation in humans with a lethal congenital syndrome.

Koutsopoulos OS, Kretz C, Weller CM, Roux A, Mojzisova H, Böhm J, Koch C, Toussaint A, Heckel E, Stemkens D, Ter Horst SA, Thibault C, Koch M, Mehdi SQ, Bijlsma EK, Mandel JL, Vermot J, Laporte J.
Eur J Hum Genet. 2013;Jun;21(6):637-42

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2012


Phosphatase-dead myotubularin ameliorates X-linked centronuclear myopathy phenotypes in mice.

Amoasii L, Bertazzi DL, Tronchère H, Hnia K, Chicanne G, Rinaldi B, Cowling BS, Ferry A, Klaholz B, Payrastre B, Laporte J, Friant S.
Plos Genet. 2012;2012;8(10):e1002965

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Control of ground-state pluripotency by allelic regulation of Nanog.

Miyanari Y, Torres-Padilla ME.
Nature 2012;Feb 12;483(7390):470-3

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Epilepsy gene LGI1 regulates postnatal developmental remodeling of retinogeniculate synapses

Zhou YD, Zhang D, Ozkaynak E, Wang X, Kasper EM, Leguern E, Baulac S, Anderson MP
J Neurosci 2012;Jan 18;32(3):903-10

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Primary T-tubule and autophagy defects in the phosphoinositide phosphatase Jumpy/MTMR14 knockout mice muscle.

Hnia K, Kretz C, Amoasii L, Böhm J, Liu X, Messaddeq N, Qu CK, Laporte J.
Adv Biol Regul. 2012;Jan;52(1):98-107

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LITAF (SIMPLE) regulates Wallerian degeneration after injury but is not essential for peripheral nerve development and maintenance: implications for Charcot-Marie-Tooth disease.

Somandin C, Gerber D, Pereira JA, Horn M, Suter U.
Glia 2012;Oct;60(10):1518-28.

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DYRK1A: a master regulatory protein controlling brain growth.

Guedj F, Pereira PL, Najas S, Barallobre MJ, Chabert C, Souchet B, Sebrie C, Verney C, Herault Y, Arbones M, Delabar JM.
Neurobiol Dis. 2012;Apr;46(1):190-203.

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An epigenetic silencing pathway controlling T helper 2 cell lineage commitment

Allan RS, Zueva E, Cammas F, Schreiber HA, Masson V, Belz GT, Roche D, Maison C, Quivy JP, Almouzni G, Amigorena S.
Nature 2012;Jul 12;487(7406):249-53.

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The nuclear receptor REV-ERBalpha-/- is required for the daily balance of carbohydrate and lipid metabolism

Julien Delezie, Stéphanie Dumont, Hugues Dardente, Hugues Oudart, Aline Gréchez-Cassiau, Paul Klosen, Michèle Teboul, Franck Delaunay, Paul Pévet and Etienne Challet
Faseb 2012;26, 3321–3335

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The in vivo Down syndrome genomic library in mouse.

Herault Y, Duchon A, Velot E, Maréchal D, Brault V.
Prog Brain Res. 2012;197:169-97.

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Pharmacological modulation of the retinal unfolded protein response in Bardet-Biedl syndrome reduces apoptosis and preserves light detection ability

Mockel A, Obringer C, Hakvoort TBM, Seeliger M, Lamers WH, Stoetzel C, Dollfus H, Marion V
Journal Of Biological Chemistry 2012;M112.386821

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Myelin is dependent on the Charcot-Marie-Tooth Type 4H disease culprit protein FRABIN/FGD4 in Schwann cells

Horn M, Baumann R, Pereira JA, Sidiropoulos PN, Somandin C, Welzl H, Stendel C, Lühmann T, Wessig C, Toyka KV, Relvas JB, Senderek J, Suter U
Brain. 2012;Dec;135(Pt 12):3567-83

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Structural and Functional Concepts in Current Mouse Phenotyping and Archiving Facilities

Kollmus H, Post R, Brielmeier M, Fernández J, Fuchs H, McKerlie C, Montoliu L, Otaegui PJ, Rebelo M, Riedesel H, Ruberte J, Sedlacek R, de Angelis MH, Schughart K.
J Am Assoc Lab Anim Sci. 2012;Jul;51(4):418-35.

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BBS-Induced Ciliary Defect Enhances Adipogenesis, Causing Paradoxical Higher-Insulin Sensitivity, Glucose Usage, and decreased Inflammatory responseBS

Marion V, Mockel A, De Melo C, Obringer C, Claussmann A, Simon A, Messaddeq N, Durand M, Dupuis L, Loeffer JP, King P, Mutter-schmidt C, Petrovsky N, Stoetzel C, Dollfuss H
Cell Metabolism 2012;Sep 5;16(3):363-77

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The App-Runx1 region is critical for birth defects and electrocardiographic dysfunctions observed in a Down syndrome mouse model.

Raveau M, Lignon JM, Nalesso V, Duchon A, Groner Y, Sharp AJ, Dembele D, Brault V, Hérault Y.
Plos Genetic 2012;May;8(5):e1002724

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Analysis of active chromatin modifications in early mammalian embryos reveals uncoupling of H2A.Z acetylation and H3K36 trimethylation from embryonic genome activation.

Bošković A, Bender A, Gall L, Ziegler-Birling C, Beaujean N, Torres-Padilla ME.
Epigenetics 2012;Jul;7(7):747-57

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2011


Targeted deletion of liver glucose-6 phosphatase mimics glycogen storage disease type 1a including development of multiple adenomas

Mutel E, Abdul-Wahed A, Ramamonjisoa N, Stefanutti A, Houberdon I, Cavassila S, Pilleul F, Beuf O, Gautier-Stein A, Penhoat A, Mithieux G, Rajas F
J Hepatol 2011;Mar;54(3):529-37

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Roles of transactivating functions 1 and 2 of estrogen receptor-alpha in bone.

Börjesson AE, Windahl SH, Lagerquist MK, Engdahl C, Frenkel B, Movérare-Skrtic S, Sjögren K, Kindblom JM, Stubelius A, Islander U, Antal MC, Krust A, Chambon P, Ohlsson C.
Proc Natl Acad Sci U S A 2011;Apr 12;108(15):6288-93

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Activation function 2 (AF2) of estrogen receptor-alpha is required for the atheroprotective action of estradiol but not to accelerate endothelial healing.

Billon-Galés A, Krust A, Fontaine C, Abot A, Flouriot G, Toutain C, Berges H, Gadeau AP, Lenfant F, Gourdy P, Chambon P, Arnal JF.
Proc Natl Acad Sci U S A 2011;Aug 9;108(32):13311-6

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Genetic ablation of delta opioid receptors in nociceptive sensory neurons increases chronic pain and abolishes opioid analgesia.

Gaveriaux-Ruff C, Nozaki C, Nadal X, Hever XC, Weibel R, Matifas A, Reiss D, Filliol D, Nassar MA, Wood JN, Maldonado R, Kieffer BL.
Pain 2011;Jun;152(6):1238-48.

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Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression

Boehler C, Gauthier LR, Mortusewicz O, Biard DS, Saliou JM, Bresson A, Sanglier-Cianferani S, Smith S, Schreiber V, Boussin F, Dantzer F
Proc Natl Acad Sci U S A 2011;Feb 15;108(7):2783-8

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A bacterial protein targets the BAHD1 chromatin complex to stimulate type III interferon response.

Lebreton A, Lakisic G, Job V, Fritsch L, Tham TN, Camejo A, Matteï PJ, Regnault B, Nahori MA, Cabanes D, Gautreau A, Ait-Si-Ali S, Dessen A, Cossart P, Bierne H.
Science 2011;Mar 11;331(6022):1319-21

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Prmt2 regulates the lipopolysaccharide-induced responses in lungs and macrophages.

Dalloneau E, Pereira PL, Brault V, Nabel EG, Hérault Y.
J Immunol. 2011;Nov 1;187(9):4826-34.

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Protein-induced satiety is abolished in the absence of intestinal gluconeogenesis

Penhoat A, Mutel E, Amigo-Correig M, Pillot B, Stefanutti A, Rajas F, Mithieux G
Physiol Behav 2011;Nov 30;105(1):89-93

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Impaired emotional-like behavior and serotonergic function during protracted abstinence from chronic morphine.

Goeldner C, Lutz PE, Darcq E, Halter T, Clesse D, Ouagazzal AM, Kieffer BL.
Biol Psychiatry. 2011;Feb 1;69(3):236-44

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Characterization of PTZ-induced seizure susceptibility in a down syndrome mouse model that overexpresses CSTB.

Brault V, Martin B, Costet N, Bizot JC, Hérault Y.
Plos One 2011;6(11):e27845

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Identification of the translocation breakpoints in the Ts65Dn and Ts1Cje mouse lines: relevance for modeling Down syndrome.

Duchon A, Raveau M, Chevalier C, Nalesso V, Sharp AJ, Herault Y.
Mamm Genome. 2011;Dec;22(11-12):674-84.

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The telomeric part of the human chromosome 21 from Cstb to Prmt2 is not necessary for the locomotor and short-term memory deficits observed in the Tc1 mouse model of Down syndrome

Duchon A, Pothion S, Brault V, Sharp AJ, Tybulewicz VL, Fisher EM, Herault Y.
Behav Brain Res. 2011;Mar 1;217(2):271-81

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Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia

Caberlotto E, Michel V, Foucher I, Bahloul A, Goodyear RJ, Pepermans E, Michalski N, Perfettini I, Alegria-Prévot O, Chardenoux S, Do Cruzeiro M, Hardelin JP, Richardson GP, Avan P, Weil D, Petit C
Proc Natl Acad Sci U S A 2011;Apr 5;108(14):5825-30

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Influence of endogenous opioid systems on T lymphocytes as assessed by the knockout of mu, delta and kappa opioid receptors.

Karaji AG, Reiss D, Matifas A, Kieffer BL, Gavériaux-Ruff C.
J Neuroimmune Pharmacol. 2011;Dec;6(4):608-16

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Necdin protects embryonic motoneurons from programmed cell death

Aebischer J, Sturny R, Andrieu D, Rieusset A, Schaller F, Geib S, Raoul C, Muscatelli F
Plos One 2011;6(9):e23764

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Myotubularin controls desmin intermediate filament architecture and mitochondrial dynamics in human and mouse skeletal muscle.

Hnia K, Tronchère H, Tomczak KK, Amoasii L, Schultz P, Beggs AH, Payrastre B, Mandel JL, Laporte J.
J Clin Invest. 2011;Jan;121(1):70-85.

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2010


Controlled Somatic and Germline Copy Number Variation in the Mouse Model

Yann Hérault, Arnaud Duchon, Damien Maréchal, Matthieu Raveau, Patricia L. Pereira, Emilie Dalloneau and Véronique Brault
Current Genomics 2010;11, 470-480

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A single postnatal injection of oxytocin rescues the lethal feeding behaviour in mouse newborns deficient for the imprinted Magel2 gene

Schaller F, Watrin F, Sturny R, Massacrier A, Szepetowski P, Muscatelli F
Hum Mol Genet 2010;Dec 15;19(24):4895-905.

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Electroclinical characterization of epileptic seizures in leucine-rich, glioma-inactivated 1-deficient mice

Chabrol E, Navarro V, Provenzano G, Cohen I, Dinocourt C, Rivaud-Péchoux S, Fricker D, Baulac M, Miles R, Leguern E, Baulac S
Brain 2010;Sep;133(9):2749-62

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Cochlear outer hair cells undergo an apical circumference remodeling constrained by the hair bundle shape

Etournay R, Lepelletier L, Boutet de Monvel J, Michel V, Cayet N, Leibovici M, Weil D, Foucher I, Hardelin JP, Petit C
Development 2010;Apr;137(8):1373-83

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Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice

Kumar R, Bourbon HM, de Massy B
Genes Dev. 2010;Jun 15;24(12):1266-80

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Heterochromatin formation in the mouse embryo requires critical residues of the histone variant H3.3.

Santenard A, Ziegler-Birling C, Koch M, Tora L, Bannister AJ, Torres-Padilla ME.
Nat Cell Biol 2010;Sep;12(9):853-62

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Dnmt3b recruitment through E2F6 transcriptional repressor mediates germ-line gene silencing in murine somatic tissues.

Velasco G, Hubé F, Rollin J, Neuillet D, Philippe C, Bouzinba-Segard H, Galvani A, Viegas-Péquignot E, Francastel C.
Proc Natl Acad Sci U S A. 2010;2010 May 18;107(20):9281-6

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Genetic dissection of the function of hindbrain axonal commissures.

Renier N, Schonewille M, Giraudet F, Badura A, Tessier-Lavigne M, Avan P, De Zeeuw CI, Chédotal A.
Plos Biol. 2010;Mar 9;8(3):e1000325

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Cadherin-23, myosin VIIa and harmonin, encoded by Usher syndrome type I genes, form a ternary complex and interact with membrane phospholipids

Bahloul A, Michel V, Hardelin JP, Nouaille S, Hoos S, Houdusse A, England P, Petit C
Human Molecular Genetics 2010;Volume 19

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Jarid2 and PRC2, partners in regulating gene expression.

Li G1, Margueron R, Ku M, Chambon P, Bernstein BE, Reinberg D.
Genes Dev. 2010;15;24(4):368-80.

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2009


The transactivating function 1 of estrogen receptor alpha is dispensable for the vasculoprotective actions of 17beta-estradiol.

Billon-Galés A, Fontaine C, Filipe C, Douin-Echinard V, Fouque MJ, Flouriot G, Gourdy P, Lenfant F, Laurell H, Krust A, Chambon P, Arnal JF.
Proc Natl Acad Sci U S A 2009;Feb 10;106(6):2053-8

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T-tubule disorganization and defective excitation-contraction coupling in muscle fibers lacking myotubularin lipid phosphatase.

Al-Qusairi L, Weiss N, Toussaint A, Berbey C, Messaddeq N, Kretz C, Sanoudou D, Beggs AH, Allard B, Mandel JL, Laporte J, Jacquemond V, Buj-Bello A.
Proc Natl Acad Sci U S A 2009;Nov 3;106(44):18763-8.

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TBP2 is essential for germ cell development by regulating transcription and chromatin condensation in the oocyte.

Gazdag E, Santenard A, Ziegler-Birling C, Altobelli G, Poch O, Tora L, Torres-Padilla ME.
Genes Dev. 2009;Sep 15;23(18):2210-23

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2008


Effective gene therapy of mice with congenital erythropoietic porphyria is facilitated by a survival advantage of corrected erythroid cells

Robert-Richard E, Moreau-Gaudry F, Lalanne M, Lamrissi-Garcia I, Cario-André M, Guyonnet-Dupérat V, Taine L, Ged C, de Verneuil H
Am J Hum Genet 2008;Jan;82(1):113-24

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Effects of nociceptin/orphanin FQ receptor (NOP) agonist, Ro64-6198, on reactivity to acute pain in mice: comparison to morphine.

Reiss D, Wichmann J, Tekeshima H, Kieffer BL, Ouagazzal AM.
Eur J Pharmacol. 2008;Jan 28;579(1-3):141-8.

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Successful gene therapy of mice with congenital erythropoietic porphyria

de Verneuil H, Robert-Richard E, Ged C, Mazurier F, Richard E, Moreau-Gaudry F
Med Sci (Paris) 2008;Jun-Jul;24(6-7):615-20

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Disruption of Krox20–Nab Interaction in the Mouse Leads to Peripheral Neuropathy with Biphasic Evolution

Desmazières A, Decker L, Vallat JM, Charnay P, Gilardi-Hebenstreit P.
J Neurosci. 2008; Jun 4;28(23):5891-900

View on PubMed

Sterility and absence of histopathological defects in nonreproductive organs of a mouse ERbeta-null mutant.

Antal MC, Krust A, Chambon P, Mark M.
Proc Natl Acad Sci U S A 2008;Feb 19;105(7):2433-8

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Erythropoietic porphyrias: animal models and update in gene-based therapies

Richard E, Robert-Richard E, Ged C, Moreau-Gaudry F, de Verneuil H
Curr Gene Ther 2008;Jun;8(3):176-86

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2006


Sensory defects in Necdin deficient mice result from a loss of sensory neurons correlated within an increase of developmental programmed cell death

Andrieu D, Meziane H, Marly F, Angelats C, Fernandez PA, Muscatelli F
Bmc Dev Biol 2006;20;6:56

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A knock-in mouse model of congenital erythropoietic porphyria

Ged C, Mendez M, Robert E, Lalanne M, Lamrissi-Garcia I, Costet P, Daniel JY, Dubus P, Mazurier F, Moreau-Gaudry F, de Verneuil H
Genomics 2006;Jan;87(1):84-92

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Knockin mice expressing fluorescent δ-opioid receptors uncover G protein-coupled receptor dynamics invivo

Grégory Scherrer, Petra Tryoen-Tóth, Dominique Filliol, Audrey Matifas, Delphine Laustriat, Yu Q. Cao, Allan I. Basbaum, Andrée Dierich, Jean-Luc Vonesh, Claire Gavériaux-Ruff, and Brigitte L. Kieffer
Pnas 2006;103 (25) 9691-9696

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2004


Disease progression despite early loss of polyglutamine protein expression in SCA7 mouse model.

Helmlinger D, Abou-Sleymane G, Yvert G, Rousseau S, Weber C, Trottier Y, Mandel JL, Devys D.
J Neurosci. 2004;25;24(8):1881-7

View on PubMed

Tissue-specific and inducible Cre-mediated recombination in the gut epithelium

El Marjou F., Janssen K.P., Hung-Junn Chang B., Li M., Hindie V., Chan L., Louvard D., Chambon P., Metzger D., Robine S
Genesis 2004;Jul;39(3):186-93.

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2002


Progressive retinal degeneration and dysfunction in R6 Huntington's disease mice.

Helmlinger D, Yvert G, Picaud S, Merienne K, Sahel J, Mandel JL, Devys D.
Hum Mol Genet 2002;15;11(26):3351-9

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The lipid phosphatase myotubularin is essential for skeletal muscle maintenance but not for myogenesis in mice.

Buj-Bello A, Laugel V, Messaddeq N, Zahreddine H, Laporte J, Pellissier JF, Mandel JL.
Proc Natl Acad Sci U S A 2002;Nov 12;99(23):15060-5

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