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Aneuploidy: from a physiological mechanism of variance to Down syndrome

Dierssen M., Herault Y., Estivill X.
Physiol Rev 2009 Jul;89(3):887-920

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A new mouse model for the trisomy of the Abcg1-U2af1 region reveals the complexity of the combinatorial genetic code of down syndrome

Pereira P.L., Magnol L., Sahun I., Brault V., Duchon A., Prandini P., Gruart A., Bizot J.C., Chadefaux-Vekemans B., Deutsch S., Trovero F., Delgado-Garcia J.M., Antonarakis S.E., Dierssen M., Herault Y.
Hum Mol Genet 2009 Dec 15;18(24):4756-69

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A ruthenium-containing organometallic compound reduces tumor growth through induction of the endoplasmic reticulum stress gene CHOP.

Meng X, Leyva ML, Jenny M, Gross I, Benosman S, Fricker B, Harlepp S, Hébraud P, Boos A, Wlosik P, Bischoff P, Sirlin C, Pfeffer M, Loeffler JP, Gaiddon C.
Cancer Res 2009 Jul 1;69(13):5458-66

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Brain structures implicated in the four-plate test in naive and experienced Swiss mice using injection of diazepam and the 5-HT2A agonist DOI.

Petit-Demoulière B, Massé F, Cogrel N, Hascoët M, Bourin M.
Behav Brain Res 2009 Dec 1;204(1):200-5

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DYRK1A, a novel determinant of the methionine-homocysteine cycle in different mouse models overexpressing this Down-syndrome-associated kinase

Noll C., Planque C., Ripoll C., Guedj F., Diez A., Ducros V., Belin N., Duchon A., Paul J.L., Badel A., de Freminville B., Grattau Y., Blehaut H., Herault Y., Janel N., Delabar J.M.
Plos One 2009 ;4(10):e7540

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Efficient temporally-controlled targeted mutagenesis in smooth muscle cells of the adult mouse

Wendling O., Bornert J.M., Chambon P., Metzger D.
Genesis 2009 Oct 21;47(1):14-18

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EMMA--mouse mutant resources for the international scientific community

Wilkinson P., Sengerova J., Matteoni R., Chen C.K., Soulat G., Ureta-Vidal A., Fessele S., Hagn M., Massimi M., Pickford K., Butler R.H., Marschall S., Mallon A.M., Pickard A., Raspa M., Scavizzi F., Fray M., Larrigaldie V., Leyritz J., Birney E., Tocchini-Valentini G.P., Brown S., Herault Y., Montoliu L., de Angelis M.H., Smedley D.
Nucleic Acids Res 2009 Jan;38(Database issue):D570-6

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Fork stalling and template switching as a mechanism for polyalanine tract expansion affecting the DYC mutant of HOXD13, a new murine model of synpolydactyly

Cocquempot O., Brault V., Babinet C., Herault Y.
Genetics 2009 Sep;183(1):23-30

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Gene expression signature of cerebellar hypoplasia in a mouse model of Down syndrome during postnatal development

Laffaire J., Rivals I., Dauphinot L., Pasteau F., Wehrle R., Larrat B., Vitalis T., Moldrich R.X., Rossier J., Sinkus R., Herault Y., Dusart I., Potier M.C.
Bmc Genomics 2009 ;10():138

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Heme oxygenase-1 accelerates cutaneous wound healing in mice

Grochot-Przeczek A., Lach R., Mis J., Skrzypek K., Gozdecka M., Sroczynska P., Dubiel M., Rutkowski A., Kozakowska M., Zagorska A., Walczynski J., Was H., Kotlinowski J., Drukala J., Kurowski K., Kieda C., Herault Y., Dulak J., Jozkowicz A.
Plos One 2009 ;4(6):e5803

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Identification of the UBP1 locus as a critical blood pressure determinant using a combination of mouse and human genetics.

Koutnikova H, Laakso M, Lu L, Combe R, Paananen J, Kuulasmaa T, Kuusisto J, Häring HU, Hansen T, Pedersen O, Smith U, Hanefeld M, Williams RW, Auwerx J.
Plos Genet 2009 Aug;5(8):e1000591

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Ppargamma2 is a key driver of longevity in the mouse

Argmann C., Dobrin R., Heikkinen S., Auburtin A., Pouilly L., Cock T.A., Koutnikova H., Zhu J., Schadt E.E., Auwerx J.
Plos Genet 2009 Dec;5(12):e1000752

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Proliferation deficits and gene expression dysregulation in Down's syndrome (Ts1Cje) neural progenitor cells cultured from neurospheres

Moldrich R.X., Dauphinot L., Laffaire J., Vitalis T., Herault Y., Beart P.M., Rossier J., Vivien D., Gehrig C., Antonarakis S.E., Lyle R., Potier M.C.
J Neurosci Res 2009 Nov 1;87(14):3143-52

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Site-specific recombinases for manipulation of the mouse genome

Birling M.C., Gofflot F., Warot X.
Methods Mol Biol 2009 ;561():245-63

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The Histone Deacetylase SIRT1 Controls Male Fertility in Mice Through Regulation of Hypothalamic-Pituitary Gonadotropin Signaling

Kolthur-Seetharam U., Teerds K., Rooij D.G., Wendling O., McBurney M., Sassone-Corsi P., Davidson I.
Biol Reprod 2009 Feb;80(2):384-91

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The Pro12Ala PPARgamma2 Variant Determines Metabolism at the Gene-Environment Interface

Heikkinen S., Argmann C., Feige J.N., Koutnikova H., Champy M.F., Dali-Youcef N., Schadt E.E., Laakso M., Auwerx J.
Cell Metab 2009 Jan 7;9(1):88-98

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