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Aggregation and Amyloidogenicity of the Nuclear Coactivator Binding Domain of CREB-Binding Protein.

Garcia AM, Giorgiutti C, El Khoury Y, Bauer V, Spiegelhalter C, Leize-Wagner E, Hellwig P, Potier N, Torbeev V
Chemistry 2020 Aug 6;26(44):9889-9899

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Antinociceptive Effects of Potent, Selective and Brain Penetrant Muscarinic M4 Positive Allosteric Modulators in Rodent Pain Models.

Grauer SM(1), Sanoja R(2), Poulin D(3), Rashid H(3), Jochnowitz N(4), Calhoun M(4), Zwilling D(4), Varty GB(4), Rosahl TW(4), Meziane H(5), Mittlelhaeuser C(5), Mazzola R(4), Morrow J(2), Smith SM(2), Henze D(2), Marcus J(2).
Brain Res 2020 Mar 29:146814

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BAHD1 haploinsufficiency results in anxiety-like phenotypes in male mice.

Pourpre R, Naudon L, Meziane H, Lakisic G, Jouneau L, Varet H, Legendre R, Wendling O, Selloum M, Proux C, Coppée JY, Herault Y, Bierne H
Plos One 2020 ;15(5):e0232789

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Conditional switching of KIF2A mutation provides new insights into cortical malformations pathogeny.

Gilet J(1)(2)(3)(4), Ivanova E(1)(2)(3)(4), Trofimova D(3), Rudolf G(1)(2)(3)(4), Meziane H(4), Broix L(1)(2)(3)(4), Drouot N(1)(2)(3)(4), Courraud J(1)(2)(3)(4), Skory V(1)(2)(3)(4), Voulleminot P(5), Osipenko M(1)(2)(3)(4), Bahi-Buisson N(6), Yalcin B(1)(2)(3)(4), Birling MC(4), Hinckelmann MV(1)(2)(3)(4), Kwok BH(7)(8), Allingham JS(3), Chelly J(1)(2)(3)(4)(5)(9)(10).
Hum Mol Genet 2020 Jan 10

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Genetic quality assurance and genetic monitoring of laboratory mice and rats: FELASA Working Group Report.

Benavides F, Rülicke T, Prins JB, Bussell J, Scavizzi F, Cinelli P, Herault Y, Wedekind D
Lab Anim 2020 Apr;54(2):135-148

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High-throughput discovery of genetic determinants of circadian misalignment.

Zhang T(1), Xie P(1), Dong Y(1), Liu Z(1), Zhou F(1), Pan D(1), Huang Z(1), Zhai Q(1), Gu Y(1), Wu Q(2)(3), Tanaka N(4), Obata Y(4), Bradley A(5), Lelliott CJ(5); Sanger Institute Mouse Genetics Project, Nutter LMJ(6), McKerlie C(6), Flenniken AM(6), Champy MF(7), Sorg T(7), Herault Y(7), Angelis MH(8)(9), Durner VG(8), Mallon AM(10), Brown SDM(10), Meehan T(11), Parkinson HE(11), Smedley D(12), Lloyd KCK(13), Yan J(14), Gao X(14), Seong JK(15), Wang CL(16), Sedlacek R(9), Liu Y(17), Rozman J(8)(9)(18), Yang L(1), Xu Y(1)(3).
Plos Genet 2020 Jan 13;16(1):e1008577

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Human and mouse essentiality screens as a resource for disease gene discovery.

Cacheiro P(1), Muñoz-Fuentes V(2), Murray SA(3), Dickinson ME(4)(5), Bucan M(6), Nutter LMJ(7), Peterson KA(3), Haselimashhadi H(2), Flenniken AM(8), Morgan H(9), Westerberg H(9), Konopka T(1), Hsu CW(4), Christiansen A(4), Lanza DG(5), Beaudet AL(5), Heaney JD(5), Fuchs H(10), Gailus-Durner V(10), Sorg T(11), Prochazka J(12), Novosadova V(12), Lelliott CJ(13), Wardle-Jones H(13), Wells S(9), Teboul L(9), Cater H(9), Stewart M(9), Hough T(9), Wurst W(14)(15)(16), Sedlacek R(12), Adams DJ(13), Seavitt JR(5), Tocchini-Valentini G(17), Mammano F(17), Braun RE(3), McKerlie C(7)(18), Herault Y(19), de Angelis MH(10)(20)(21), Mallon AM(9), Lloyd KCK(22), Brown SDM(9), Parkinson H(2), Meehan TF(2), Smedley D(23); Genomics England Research Consortium; International Mouse Phenotyping Consortium.
Nat Commun 2020 Jan 31;11(1):655

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Introduction to Mammalian Genome Special Issue: Epigenetics.

Beckers J, Teperino R, Hérault Y, Hrabé de Angelis M
Mamm Genome 2020 Jun;31(5-6):117-118

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Modeling Down syndrome in animals from the early stage to the 4.0 models and next.

Muñiz Moreno MDM, Brault V, Birling MC, Pavlovic G, Herault Y
Prog Brain Res 2020 ;251():91-143

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PATHBIO: an international training program for precision mouse phenotyping.

Ruberte J, Schofield PN, Brakebusch C, Vogel P, Herault Y, Gracia G, McKerlie C, Hrabĕ de Angelis M, Hagn M, Sundberg JP
Mamm Genome 2020 Feb;31(1-2):49-53

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Soft windowing application to improve analysis of high-throughput phenotyping data.

Haselimashhadi H, Mason JC, Munoz-Fuentes V, López-Gómez F, Babalola K, Acar EF, Kumar V, White J, Flenniken AM, King R, Straiton E, Seavitt JR, Gaspero A, Garza A, Christianson AE, Hsu CW, Reynolds CL, Lanza DG, Lorenzo I, Green JR, Gallegos JJ, Bohat R, Samaco RC, Veeraragavan S, Kim JK, Miller G, Fuchs H, Garrett L, Becker L, Kang YK, Clary D, Cho SY, Tamura M, Tanaka N, Soo KD, Bezginov A, About GB, Champy MF, Vasseur L, Leblanc S, Meziane H, Selloum M, Reilly PT, Spielmann N, Maier H, Gailus-Durner V, Sorg T, Hiroshi M, Yuichi O, Heaney JD, Dickinson ME, Wolfgang W, Tocchini-Valentini GP, Lloyd KCK, McKerlie C, Seong JK, Yann H, de Angelis MH, Brown SDM, Smedley D, Flicek P, Mallon AM, Parkinson H, Meehan TF
Bioinformatics 2020 Mar 1;36(5):1492-1500

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