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Scientific Organizers: J. Keith Joung, Massachusetts General Hospital, USA Emmanuelle Charpentier, Max Planck Institute for Infection Biology and Humboldt University, Germany and The Laboratory for Molecular Infection Medicine, Sweden Olivier Danos, Biogen, USA.

Precision genome engineering technologies enable targeted, highly efficient alteration of DNA sequences in living cells or organisms. Given their customizable nature, these technologies promise to be broadly useful both as biomedical research tools and as novel therapeutics for gene-based diseases. Given the rapidity with which this field moves, it is challenging for both newcomers and experts alike to stay updated with all of the latest advances. The goal of this Keystone Symposia meeting is to bring together scientists from academia and industry with diverse but relevant expertise in a setting conducive to discussion of new results and potential collaborative efforts. Invited talks will cover a wide range of topics ranging from fundamental basic science through to clinical translation studies. Attendees of this meeting will have the opportunity to hear about the latest findings in this fast-paced field and to establish collaborations with scientists who have complementary expertise.

Session Topics:

• • (Basic) Science of Recombination and DNA Repair
• • Latest Advances in Genome-Editing Nuclease Technologies I & II
• • Biology of CRISPR Systems
• • Research Applications of Genome and Epigenome Engineering I & II
• • Novel Technologies for Therapeutic Application of Genome Engineering
• • Therapeutic Applications of Genome Engineering

PHENOMIN-ICS will attend this meeting. Meet us and visit the poster "Efficient and rapid generation of large genomic variants in rat and mice by CRISPR/Cas9 genome editing"