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Hematological analysis of blood determines blood cell counts (leukocytes, erythrocytes and platelets) and gives hemoglobin levels. Additional hematological parameters (hematocrit, mean cell volume, mean corpuscular hemoglobin, mean cell hemoglobin concentration) can be calculated. The different white blood cells (WBC) lines: neutrophils, lymphocytes, monocytes, eosinophils, and basophils are also identified and counted.
CBC is performed on an Advia 120 (Siemens AG, Erlangen, Germany) with Veterinary software.
Within the same cohort, approximately 9 mice per group are recommended for reliable data analysis.
Determination of prothrombine time, activated partial thromboplastin time and fibrinogen activity.
ST4 semi automated coagulometer (Diagnostiqua Stago, Gennevilliers, France).
It is recommended to collect blood by intra-cardiac puncture.
Within the same cohort, approximately 9 mice per group are recommended for reliable data analysis.
Blood hematology in different mouse strains at the age of 3 months (Platelets)
Blood hematology in different mouse strains at the age of 3 months (Leukocytes)
Blood hematology in different mouse strains at the age of 3 months (Erythrocytes)
